Ermolina G B, Degteva G K, Nosova T V, Shubina Z V
Antibiot Khimioter. 1991 Feb;36(2):19-21.
The beta-lactamase activity of staphylococci isolated from the nasopharynx and skin of children with destructive affections of the lungs and from blood of patients with cardiovascular diseases subjected to surgical operations was determined with acidometric and microbiological procedures. Interrelation between synthesis of beta-lactamase by the staphylococcal strains and their resistance to beta-lactam antibiotics was demonstrated. No correlation of the antibiotic resistance and the taxonomic position of the staphylococcal strains was observed.
采用酸度测定法和微生物学方法，对从患有肺部破坏性疾病儿童的鼻咽部和皮肤分离出的葡萄球菌，以及接受外科手术的心血管疾病患者血液中的葡萄球菌的β-内酰胺酶活性进行了测定。结果表明葡萄球菌菌株β-内酰胺酶的合成与其对β-内酰胺抗生素的耐药性之间存在相互关系。未观察到葡萄球菌菌株的抗生素耐药性与其分类学地位之间存在相关性。
