一种新的淋巴样细胞系，Reh 6，具有非T和非B细胞的特征，缺乏爱泼斯坦-巴尔病毒基因组，源自人类急性淋巴细胞白血病。
A new lymphoid cell line, Reh 6, with characteristics of non-T and non-B cells, lacking the Epstein-Barr virus genome and derived from human acute lymphoblastic leukemia.
作者信息
Kayibanda B, Rosenfeld C, Goutner A, Bornkamm G W
出版信息
Intervirology. 1978;9(5):316-20. doi: 10.1159/000148950.
A new lymphoid cell line, Reh 6, has been established from the peripheral blood of a patient with acute lymphocytic leukemia. Reh 6 cells were assayed for the presence of Epstein-Barr virus (EBV) DNA by nucleic acid hybridization and for Epstein-Barr nuclear antigen (EBNA) by the immunofluorescence test. Reassociation kinetics between in vitro [3H]-labeled EBV DNA and Reh 6 cell DNA indicated the absence of detectable amounts of EBV DNA in Reh 6 cell DNA. In addition, attempts to detect EBNA by the immunofluorescence test in Reh 6 cells were unsuccessful. Thus, this new lymphoid cell line apparently lacks the EBV genome.
一种新的淋巴样细胞系Reh 6已从一名急性淋巴细胞白血病患者的外周血中建立。通过核酸杂交检测Reh 6细胞中是否存在爱泼斯坦-巴尔病毒（EBV）DNA，并通过免疫荧光试验检测爱泼斯坦-巴尔核抗原（EBNA）。体外[3H]标记的EBV DNA与Reh 6细胞DNA之间的重缔合动力学表明，Reh 6细胞DNA中未检测到可检测量的EBV DNA。此外，通过免疫荧光试验在Reh 6细胞中检测EBNA的尝试未成功。因此，这种新的淋巴样细胞系显然缺乏EBV基因组。
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