Yakir Y, Kook A I, Schlesinger M, Trainin N
Isr J Med Sci. 1977 Dec;13(12):1191-6.
The exposure of human peripheral blood lymphocytes to thymus hormone causes an increase in the intracellular cyclic AMP level in these cells. Studies of the thymus-hormone-induced changes in cellular cyclic AMP levels revealed that cord blood lymphocytes contain significantly more target cells for the hormone than adult peripheral blood lymphocytes. The data obtained also suggest that the interaction between the hormone and its target cell is not readily reversible and that only a certain proportion of target cells in a given population of lymphocytes can be activated by a constant and limited amount of thymus humoral factor.
人类外周血淋巴细胞暴露于胸腺激素会导致这些细胞内的环磷酸腺苷（cAMP）水平升高。对胸腺激素诱导的细胞cAMP水平变化的研究表明，脐带血淋巴细胞所含的该激素靶细胞比成人外周血淋巴细胞显著更多。所获得的数据还表明，激素与其靶细胞之间的相互作用不易逆转，并且在给定的淋巴细胞群体中，只有一定比例的靶细胞能够被恒定且有限量的胸腺体液因子激活。
