Pellet H, Buenerd A, Minaire E, Lacavalerie B, Donne C
Department of Histology, Grange-Blanche Faculty, Lyon, France.
Diagn Cytopathol. 1991;7(1):27-31. doi: 10.1002/dc.2840070109.
The authors evaluated red blood cell (RBC) morphology by phase contrast microscopy and identified casts and lipidic material in 4,448 urine sediments (US). Microhematuria was discovered on systematic examination in 1,186 apparently healthy patients (group I). Another 4,362 patients (group II) with microscopic or gross hematuria were being treated or evaluated for various renal or extrarenal diseases (renal transplantation excepted). Glomerular hematuria (GH) was observed in 93.1% of group I patients and in 58.0% of group II patients. GH and non-GH were observed together in 0.6% of cases. The origin of hematuria remained uncertain in 11.6% of cases. In GH, the other cytological findings were as follows: RBC casts were seen in 5.3% of group I and 20.5% of group II; granular and/or cellular casts were seen in 12.8% of group I and 39.6% of group II; and lipidic material was seen in 0.6% of group I and 8.8% of group II. Both groups showed a higher frequency of RBC casts, granular and/or cellular casts, and lipidic material in patients under 20. This method of investigation of urine, which is simple, rapid, inexpensive, and noninvasive, provides useful information for the clinician and avoids unnecessary investigations.
作者通过相差显微镜评估红细胞（RBC）形态，并在4448份尿沉渣（US）中鉴定管型和脂质物质。在1186例看似健康的患者（I组）的系统检查中发现了镜下血尿。另外4362例有镜下或肉眼血尿的患者（II组）正在接受各种肾脏或肾外疾病的治疗或评估（肾移植除外）。I组93.1%的患者和II组58.0%的患者观察到肾小球性血尿（GH）。0.6%的病例同时观察到GH和非GH。11.6%的病例血尿来源仍不确定。在GH中，其他细胞学发现如下：I组5.3%的患者和II组20.5%的患者可见RBC管型；I组12.8%的患者和II组39.6%的患者可见颗粒和/或细胞管型；I组0.6%的患者和II组8.8%的患者可见脂质物质。两组在20岁以下患者中RBC管型、颗粒和/或细胞管型以及脂质物质的出现频率更高。这种简单、快速、廉价且无创的尿液检查方法为临床医生提供了有用信息，并避免了不必要的检查。
