Hildebrandt F, Fecht A, König B, Brandis M
Zentrum für Kinderheilkunde, Philipps-Universität Marburg.
Monatsschr Kinderheilkd. 1988 Jan;136(1):10-6.
We examined 70 urinary sediments of 35 children with non-glomerular hematuria (NGH) and 65 urinary sediments of 17 children with glomerular hematuria (GH) by phase-contrast microscopy at 1,000 X magnification. In each urinary sediment 200 erythrocytes were classified into 18 types of "non-glomerular erythrocytes" and 15 types of "glomerular erythrocytes". According to the percentage of greatly altered erythrocytes the urinary finding was termed isomorphic, mixed or dysmorphic. In 91% of the urinary sediments of patients with NGH the erythrocyte pattern was isomorphic, and in 91% of the urinary sediments of children with GH it was dysmorphic. 9 types of non-glomerular erythrocytes and 10 types of glomerular erythrocytes constituted 94.5% of all 26,809 erythrocytes examined. Torocytes (doughnut-like cells) can be considered characteristic for GH. This study demonstrates a high specificity of this method in discriminating NGH from GH. The exact morphological description of urinary erythrocytes allows the method to be reproducible. For future use examiners can concentrate on the 19 commonest erythrocyte types.
我们使用相差显微镜在1000倍放大倍数下检查了35例非肾小球性血尿（NGH）患儿的70份尿沉渣以及17例肾小球性血尿（GH）患儿的65份尿沉渣。在每份尿沉渣中，将200个红细胞分为18种“非肾小球性红细胞”类型和15种“肾小球性红细胞”类型。根据显著改变的红细胞百分比，将尿液检查结果分为同形、混合或异形。在NGH患者的91%尿沉渣中，红细胞形态为同形，而在GH患儿的91%尿沉渣中，红细胞形态为异形。9种非肾小球性红细胞和10种肾小球性红细胞占所有检查的26809个红细胞的94.5%。环行红细胞（甜甜圈样细胞）可被视为GH的特征性表现。本研究表明该方法在区分NGH和GH方面具有高度特异性。对尿红细胞的确切形态学描述使该方法具有可重复性。为了今后使用，检查人员可以专注于19种最常见的红细胞类型。
