Brown J J, Lee J M, Lee J K, Van Lom K J, Malchow S C
Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110.
Radiology. 1991 Jun;179(3):675-9. doi: 10.1148/radiology.179.3.2027973.
Magnetic resonance (MR) examinations of 43 patients with 95 focal hepatic lesions (diameter, greater than 1 cm) were analyzed for lesion shape, homogeneity, and relative signal intensity compared with normal liver parenchyma, spleen, and skeletal muscle. On T1-weighted, balanced, and T2-weighted images, most metastases (74%), cavernous hemangiomas (76%), and cysts (82%) were smooth and round or oval, while the hepatocellular carcinomas all had irregular borders (40%) or were lobulated (60%). All lesions with irregular borders were malignant. Seventy percent of metastatic lesions, 85% of cavernous hemangiomas, and 100% of simple hepatic cysts were of homogeneous signal intensity, while 60% of hepatocellular carcinomas were inhomogeneous. Logistic regression analysis of multiple lesion characteristics showed that inhomogeneous lesions had a high likelihood of malignancy, while markedly hyperintense lesions had a very low probability of being malignant, regardless of other traits. Homogeneous lesions that were isointense or hyperintense compared with spleen on balanced images but were not markedly hyperintense on T2-weighted images also had a high likelihood of malignancy.
对43例患有95个肝脏局灶性病变（直径大于1 cm）的患者进行了磁共振（MR）检查，分析了病变的形状、均匀性以及与正常肝实质、脾脏和骨骼肌相比的相对信号强度。在T1加权、平衡加权和T2加权图像上，大多数转移瘤（74%）、海绵状血管瘤（76%）和囊肿（82%）呈光滑的圆形或椭圆形，而肝细胞癌均有不规则边界（40%）或呈分叶状（60%）。所有边界不规则的病变均为恶性。70%的转移瘤、85%的海绵状血管瘤和100%的单纯肝囊肿信号强度均匀，而60%的肝细胞癌信号强度不均匀。对多种病变特征进行逻辑回归分析表明，无论其他特征如何，信号强度不均匀的病变恶性可能性高，而明显高信号的病变恶性概率极低。在平衡加权图像上与脾脏等信号或高信号但在T2加权图像上不明显高信号的均匀病变恶性可能性也高。
