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腹主动脉-双侧股动脉旁路移植术后的结果和生活质量。

Outcome and quality of life after aorto-bifemoral bypass surgery.

机构信息

Department of Anesthesia, Hospital de São João, Porto, Portugal.

出版信息

BMC Cardiovasc Disord. 2010 Mar 18;10:15. doi: 10.1186/1471-2261-10-15.

Abstract

BACKGROUND

Aorto-bifemoral bypass (AFB) is commonly performed to treat aorto-iliac disease and a durable long-term outcome is achieved. Most studies documenting beneficial outcomes after AFB have been limited to mortality and morbidity rates, costs and length of hospital stay (LOS). Few studies have examined the dependency of patients and how their perception of their own health changes after surgery. The aim of the present study was to evaluate outcome after AFB and to study its determinants.

METHODS

This retrospective study was carried out in the multidisciplinary Post-Anaesthesia Care Unit (PACU) with five intensive care beds. Out of 1597 intensive care patients admitted to the PACU, 75 were submitted to infrarenal AFB and admitted to these intensive care unit (ICU) beds over 2 years. Preoperative characteristics and outcome were evaluated by comparing occlusive disease with aneurysmatic disease patients. Six months after discharge, the patients were contacted to complete a Short Form-36 questionnaire (SF-36) and to have their dependency in Activities of Daily Living (ADL) evaluated. Patient's characteristics and postoperative follow-up data were compared using Mann-Whitney U test, t test for independent groups, chi-square or Fisher's exact test. Patient preoperative characteristics were evaluated for associations with mortality using a multiple logistic regression analysis.

RESULTS

The mortality rate was 12% at six months. Multivariate analysis identified congestive heart disease and APACHE II as independent determinants for mortality. Patients submitted to AFB for occlusive disease had worse SF-36 scores in role physical and general health perception. Patients submitted to AFB had worse SF-36 scores for all domains than a comparable urban population and had similar scores to other PACU patients. Sixty-six percent and 23% of patients were dependent in at least one activity in instrumental and personal ADL, respectively, but 64% reported having better general health.

CONCLUSION

This study shows that congestive heart disease and APACHE II were risk factors for mortality after AFB surgery. Survivors who have undergone AFB perceive an improved quality of life although they are more dependent in ADL tasks and have worse scores in almost all SF-36 than the population to which they belong.

摘要

背景

主动脉-双股动脉旁路术(AFB)常用于治疗主髂动脉疾病,并能实现长期稳定的效果。大多数记录 AFB 术后有益结果的研究仅限于死亡率、发病率、成本和住院时间(LOS)。很少有研究检查患者的依赖性以及他们手术后对自身健康的感知变化。本研究旨在评估 AFB 后的结果,并研究其决定因素。

方法

本回顾性研究在设有 5 张重症监护病床的多学科麻醉后护理单元(PACU)进行。在入住 PACU 的 1597 例重症监护患者中,75 例因主髂动脉阻塞性疾病接受了肾下 AFB,并在 2 年内入住这些重症监护病床。通过比较阻塞性疾病和动脉瘤性疾病患者,评估术前特征和结果。出院后 6 个月,联系患者完成简明健康调查问卷 36 项(SF-36)并评估其日常生活活动(ADL)的依赖性。使用 Mann-Whitney U 检验、独立样本 t 检验、卡方检验或 Fisher 确切概率法比较患者的特征和术后随访数据。使用多变量逻辑回归分析评估患者术前特征与死亡率的相关性。

结果

术后 6 个月的死亡率为 12%。多变量分析确定充血性心力衰竭和急性生理学与慢性健康状况评分系统 II(APACHE II)是死亡率的独立决定因素。因阻塞性疾病接受 AFB 的患者在身体角色功能和总体健康感知方面的 SF-36 评分更差。与类似的城市人群相比,接受 AFB 的患者在所有领域的 SF-36 评分都更差,与其他 PACU 患者的评分相似。66%和 23%的患者在工具性 ADL 和个人 ADL 中至少有一项活动依赖,但 64%的患者报告总体健康状况有所改善。

结论

本研究表明,充血性心力衰竭和 APACHE II 是 AFB 手术后死亡的危险因素。接受 AFB 的幸存者认为生活质量有所改善,尽管他们在 ADL 任务中依赖性更强,并且在几乎所有 SF-36 评分中都比他们所属的人群差。

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本文引用的文献

1
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