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心脏大手术后患者的生活质量与死亡率评估

Quality of life and mortality assessment in patients with major cardiac events in the postoperative period.

作者信息

Abelha Fernando José, Botelho Miguela, Fernandes Vera, Barros Henrique

机构信息

Serviço de Anestesiologia Unidade Pós-Anestésica do Hospital de São João, Porto, Portugal.

出版信息

Rev Bras Anestesiol. 2010 May-Jun;60(3):268-84. doi: 10.1016/S0034-7094(10)70035-0.

Abstract

BACKGROUND AND OBJECTIVES

Cardiovascular complications in the postoperative period are associated with high mortality and morbidity. Few studies have assessed the degree of dependence in these patients and their perception of health. The objective of this study was to assess the mortality and the quality of life in patients who developed major cardiac events (MCE) in the postoperative period.

METHOD

Retrospective study carried out in a Surgical Intensive Care Unit (SICU), between March 2006 and March 2008. The patients were assessed regarding the occurrence of CE. Six months after the hospital discharge, the Short-Form-36 (SF-36) questionnaire was filled out and dependence was assessed in relation to activities of daily living (ADL). The comparisons between independent groups of patients were carried out using Student's t test. The comparison between each variable and the occurrence of CE was carried out by logistic regression and included all patients.

RESULTS

Of the 1,280 patients that met the inclusion criteria, 26 (2%) developed MCE. The univariate analysis identified as independent determinants for the development of major cardiac events: ASA physical status, hypertension, ischemic heart disease, congestive heart disease and score of the Revised Cardiac Risk Index (RCRI). The six-month mortality after the SICU discharge was 35%. Of the 17 surviving patients, 13 completed the questionnaires. Thirty-one percent of them reported that their general health was better on the day they answered the questionnaire, when compared to 12 months before. Sixty-nine percent of the patients were dependent in instrumental ADL e 15% in personal ADL.

CONCLUSIONS

The development of MCE has a significant impact on the duration of hospital stay and mortality rates. Six months after the discharge from the SICU, more than 50% of the patients were dependent in at least one instrumental ADL.

摘要

背景与目的

术后心血管并发症与高死亡率和发病率相关。很少有研究评估这些患者的依赖程度及其健康认知。本研究的目的是评估术后发生重大心脏事件(MCE)的患者的死亡率和生活质量。

方法

于2006年3月至2008年3月在外科重症监护病房(SICU)进行回顾性研究。评估患者是否发生心脏事件(CE)。出院6个月后,填写简短健康调查问卷(SF - 36),并评估与日常生活活动(ADL)相关的依赖情况。采用学生t检验对独立患者组进行比较。通过逻辑回归对每个变量与CE的发生情况进行比较,纳入所有患者。

结果

在符合纳入标准的1280例患者中,26例(2%)发生了MCE。单因素分析确定重大心脏事件发生的独立决定因素为:美国麻醉医师协会(ASA)身体状况、高血压、缺血性心脏病、充血性心脏病和修订心脏风险指数(RCRI)评分。SICU出院后6个月的死亡率为35%。在17例存活患者中,13例完成了问卷调查。其中31%的患者报告,与12个月前相比,在回答问卷当天他们的总体健康状况更好。69%的患者在工具性日常生活活动方面存在依赖,15%的患者在个人日常生活活动方面存在依赖。

结论

MCE的发生对住院时间和死亡率有重大影响。SICU出院6个月后,超过50%的患者至少在一项工具性日常生活活动方面存在依赖。

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