吸烟与甲状腺疾病——文献综述

Smoking and thyroid disease--review of literature.

作者信息

Czarnywojtek Agata, Warmuz-Stangierska Izabela, Zdanowska Joanna, Florek Ewa, Zgorzlewicz Małgorzata, Ruchała Marek, Stangierski Adam, Sowiński Jerzy

机构信息

Chair and Department of Endocrinology and Metabolism, Internal Disease, University of Medical Sciences, Poznan.

出版信息

Przegl Lek. 2009;66(10):878-81.

PMID:20301960

Abstract

Smoking has multiple effects on the thyroid gland, which is associated with important clinical implications such as the increased risk and severity of autoimmune thyroid disorders especially Graves disease. The influence of tobacco smoking is mainly associated with pharmacological action of nicotine and also with toxins such as thiocyanate. The present review of the relevant literature concentrates on the effect of smoking on the Graves ophthalmopathy and autoimmune thyroid disorders such as Hashimoto disease. The effect of passive smoking on children and the influence of smoking on foetus are also shown. In contrast, the protective influence of tobacco on the thyroid cancer is also widely noticed. Finally, our study describes observations related to the psychological and legal aspects of smoking.

摘要

吸烟对甲状腺有多种影响，这与重要的临床意义相关，比如自身免疫性甲状腺疾病尤其是格雷夫斯病的风险和严重程度增加。吸烟的影响主要与尼古丁的药理作用以及硫氰酸盐等毒素有关。本相关文献综述着重于吸烟对格雷夫斯眼病以及自身免疫性甲状腺疾病如桥本氏病的影响。还展示了被动吸烟对儿童的影响以及吸烟对胎儿的影响。相比之下，烟草对甲状腺癌的保护作用也受到广泛关注。最后，我们的研究描述了与吸烟的心理和法律方面相关的观察结果。