Health-Care Technology Assessment Agency, Instituto de Salud Carlos III, 28029 Madrid, Spain.
Gen Hosp Psychiatry. 2010 Mar-Apr;32(2):156-63. doi: 10.1016/j.genhosppsych.2009.11.014. Epub 2010 Jan 12.
To examine nonpsychiatric hospitalizations in people with schizophrenia and to describe the epidemiological features of these admissions.
We analyzed the 2000-2004 Spanish National Hospital Discharge Registry, identified records coded for schizophrenia (295.xx), selected admissions due to non-psychiatric causes and characterized the physical diseases using the International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) system and the Deyo-Charlson Index.
From all 2000-2004 hospitalizations in subjects with schizophrenia, 21 484 records (34%) were eligible for analysis. The mean age was 53 years, 61% were men. The mean number of ICD-9-CM codes was 2.3. The main diagnoses at discharge were injury-poisoning (19%) and respiratory (15%), digestive (14%) and circulatory diseases (12%), but there were significant age and gender-related differences. Inhospital mortality was 6.9% and the mean age of death was 63 years. Circulatory, respiratory diseases and neoplasms accounted for 21%, 18% and 17% of deaths, respectively. Inhospital mortality significantly correlated with age, the Deyo-Charlson Index and some specific processes.
Hospitalizations due to physical disease are frequent among people with schizophrenia and associated with a substantial burden and in-hospital mortality in Spain. This information may prove useful for the design and application of preventive and therapeutic programs in the early and silent phases of the most prevalent physical diseases.
探讨精神分裂症患者的非精神科住院情况，并描述这些住院的流行病学特征。
我们分析了 2000-2004 年西班牙国家住院患者登记处的数据，确定了编码为精神分裂症（295.xx）的记录，选择了因非精神科原因住院的患者，并使用国际疾病分类，第 9 修订版，临床修正（ICD-9-CM）系统和 Deyo-Charlson 指数对其进行描述。
在所有患有精神分裂症的患者中，2000-2004 年的住院记录中，有 21484 条记录（34%）符合分析条件。患者的平均年龄为 53 岁，61%为男性。平均 ICD-9-CM 编码数量为 2.3。出院时的主要诊断为损伤中毒（19%）和呼吸系统疾病（15%）、消化系统疾病（14%）和循环系统疾病（12%），但存在显著的年龄和性别差异。住院死亡率为 6.9%，平均死亡年龄为 63 岁。循环系统、呼吸系统疾病和肿瘤分别占死亡的 21%、18%和 17%。住院死亡率与年龄、Deyo-Charlson 指数和某些特定的过程显著相关。
精神分裂症患者因躯体疾病住院的情况较为常见，这给西班牙带来了相当大的负担和住院死亡率。这些信息可能对设计和应用早期和隐匿阶段最常见的躯体疾病的预防和治疗方案具有重要意义。
