Rugg M D, Pickles C D, Potter D D, Roberts R C
Wellcome Brain Research Group, Department of Psychology, University of St Andrews, UK.
J Neurol Neurosurg Psychiatry. 1991 Mar;54(3):217-22. doi: 10.1136/jnnp.54.3.217.
Event-related potentials (ERPs) were recorded during auditory and visual "oddball" tasks from a patient with a severe verbal memory deficit due to a low grade infiltrating glioma which involved the full extent of the left medial temporal lobe. In both sensory modalities, the patient's oddball-evoked P300s were symmetrical and of normal amplitude. These findings are difficult to reconcile with the hypothesis that the hippocampus, or any other medial temporal structure, makes a substantial contribution to the scalp P300.
在听觉和视觉“oddball”任务期间，对一名因低度浸润性胶质瘤累及左侧颞叶内侧全部范围而患有严重言语记忆缺陷的患者记录了事件相关电位（ERP）。在两种感觉模式下，该患者的oddball诱发的P300是对称的且振幅正常。这些发现很难与海马体或任何其他内侧颞叶结构对头皮P300有重大贡献的假设相协调。
