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尿流动力学生物反馈和骨盆底肌肉生物反馈训练在治疗排尿功能障碍女性复发性尿路感染中的作用:一项随机对照前瞻性研究。

The role of uroflowmetry biofeedback and biofeedback training of the pelvic floor muscles in the treatment of recurrent urinary tract infections in women with dysfunctional voiding: a randomized controlled prospective study.

机构信息

Department of Clinic, Specialistic Sciences-Urology, Polytechnic University of the Marche Region, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Ancona, Italy.

出版信息

Urology. 2010 Jun;75(6):1299-304. doi: 10.1016/j.urology.2009.11.019. Epub 2010 Mar 19.

Abstract

OBJECTIVES

To evaluate the efficacy of a training program with uroflowmetry biofeedback and pelvic floor relaxation biofeedback on urodynamic and voiding parameters in women with dysfunctional voiding.

METHODS

Eighty-six women with recurrent urinary tract infections (UTIs) and dysfunctional voiding were randomly assigned to receive a treatment schedule as follows: uroflowmetry biofeedback (group 1), biofeedback training of the pelvic floor muscles (group 2), uroflowmetry biofeedback combined to biofeedback training of the pelvic floor muscles (group 3), no treatment (group 4). Patients were regularly evaluated by American Urological Association Symptom Index and urodynamics during the study period. All the patients were followed up for 1 year with monthly urine cultures. A further evaluation was done at month 24 by American Urological Association Symptom Index and free uroflowmetry with measurement of residual urine.

RESULTS

The prevalence of storage and emptying symptoms decreased significantly at 3, 6, and 12 months in the groups 1, 2, and 3, and remained stable during the study period. Mean flow rate, flow time, voiding volume increased significantly, whereas postvoid residual urine decreased. The prevalence of UTI decreased significantly in groups 1, 2, and 3. At month 24, storage and emptying symptoms and voiding patterns were similar to the baseline values in all the patients. The incidence of UTIs was similar to baseline values in groups 1, 2, and 3.

CONCLUSIONS

Training the voluntary control of the pelvic floor seems essential in obtaining control over the bladder function. These results reinforce the importance of pelvic floor therapy in the resolution of UTIs.

摘要

目的

评估尿流动力学生物反馈和盆底放松生物反馈训练方案对排尿功能障碍女性的尿动力学和排尿参数的疗效。

方法

86 例复发性尿路感染(UTI)和排尿功能障碍的女性患者被随机分为以下治疗组:尿流动力学生物反馈(第 1 组)、盆底肌肉生物反馈训练(第 2 组)、尿流动力学生物反馈联合盆底肌肉生物反馈训练(第 3 组)和无治疗(第 4 组)。在研究期间,患者定期通过美国泌尿协会症状指数和尿动力学进行评估。所有患者在 1 年内每月进行尿液培养,并在第 24 个月通过美国泌尿协会症状指数和自由尿流率测量残余尿进行进一步评估。

结果

第 1、2 和 3 组患者的储尿和排尿症状在 3、6 和 12 个月时显著下降,并在研究期间保持稳定。平均流速、流速时间、排尿量显著增加,而残余尿量减少。第 1、2 和 3 组 UTI 的患病率显著下降。在第 24 个月时,所有患者的储尿和排尿症状以及排尿模式与基线值相似。第 1、2 和 3 组的 UTI 发病率与基线值相似。

结论

训练盆底的自主控制对于获得对膀胱功能的控制至关重要。这些结果强调了盆底治疗在解决 UTI 中的重要性。

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