Ravelomanana T, Rabeatoandro S, Randrianaivo N, Ratsimbazafy A, Raobijaona H, Barennes H
Service de pédiatrie, Hôpital Joseph-Raseta-de-Befelatanana, CHU d'Antananarivo, BP 14 bis, Antananarivo, 101, Madagascar.
Bull Soc Pathol Exot. 2010 May;103(2):90-5. doi: 10.1007/s13149-010-0048-x. Epub 2010 Mar 20.
Since its recommendation by WHO, Oral Rehydration Solutions (ORS) contributed in reducing the rate of mortality due to acute gastroenteritis. In Madagascar, the rate of lethality imputed to gastroenteritis is about 3%. Rehydration can be performed either by using spoons which reliability is unsure because of parents' potential inobservance and child's refusal, or by nasogastric tube. The nasogastric tube may resolve these obstacles at the hospital. We realized a preliminary study to evaluate the efficacy and the safety of nasogastric tube and spoon administration of the ORS in rehydration of child with moderate post-gastroenteritis dehydration. This is an open comparative study realized in the Pediatric Unit at the Joseph-Raseta-Befelatanana Hospital from the 21 January to 21 May 2008. Main outcomes was the proportion of rehydrated children at 4 hours, other were: failure at 8 hours, duration and volume of SRO, side effects. Fifty-three children from 4-month to 4-year old among 1306 patients were recruited and forty-seven patients were included. Nine patients failed (4 children received ORS by spoon and 5 children by nasogastric tube). The use of spoon was more effective: 62.5% of the patients were rehydrated at the fourth hour versus 39.3% in nasogastric tube group (P = 0.04). Making debit constant presents difficulties in rehydration with nasogastric tube (44.4 %). Tolerance of nasogastric tube is generally good but 16.7% children get out their tube during this study. No ORS' inhalation was observed with both routes. No false passage or tube or ORS rejection was recorded in both techniques. This study shows that using spoon to rehydrate is more effective for the rehydration of moderate dehydration. The use of nasogastric tube needs more surveillance.
自世界卫生组织推荐以来,口服补液盐(ORS)有助于降低急性肠胃炎导致的死亡率。在马达加斯加,肠胃炎导致的致死率约为3%。补液可以通过使用勺子进行,但由于家长可能不注意以及孩子拒绝,其可靠性不确定,也可以通过鼻胃管进行。鼻胃管在医院可能解决这些障碍。我们开展了一项初步研究,以评估鼻胃管和用勺子给予ORS对中度肠胃炎后脱水儿童进行补液的疗效和安全性。这是一项开放对比研究于2008年1月21日至5月21日在约瑟夫 - 拉塞塔 - 贝费拉塔纳纳医院儿科病房开展。主要结局是4小时时补液成功儿童的比例,其他结局包括:8小时时补液失败、ORS补充量和持续时间、副作用情况。在1306例患者中招募了53名4个月至4岁儿童,47例患者被纳入研究对象。9例患者补液失败(4例儿童通过勺子接受ORS,5例儿童通过鼻胃管接受ORS)。使用勺子更有效:第四小时时62.5%的患者补液成功,而鼻胃管组为39.3%(P =0.04)。鼻胃管补液时保持恒定流速存在困难(44.4%))。鼻胃管的耐受性总体良好,但在本研究期间16.7%的儿童拔出了管子。两种途径均未观察到ORS吸入情况。两种技术均未记录到误插或管子或ORS排斥情况。本研究表明,对于中度脱水的补液治疗,使用勺子补液更有效。鼻胃管的使用需要更多监测