Ozalay Metin, Sahin Orcun, Derincek Alihan, Onay Ulas, Turunc Tugba, Uysal Mustafa
From BaskentUniversity Hospital and Malazgirt State Hospital, Ankara, Turkey.
Acta Orthop Belg. 2010 Feb;76(1):100-6.
Debridement is warranted for the treatment of nontuberculous spondylodiscitis in case of neurological compromise, deformity, instability, abscess formation, extensive destruction, intractable pain or failure of medical management. The additional use of instrumentation is still controversial, but might fight infection and yield stability. The purpose of this retrospective study was to evaluate the outcome of 16 cases of non-tuberculous thoracic or lumbar spondylodiscitis treated with anterior debridement and reconstruction (tricortical graft or titanium mesh cage), combined with single-stage posterior instrumentation and grafting. The pathogens identified were: Brucella (5), coagulase-negative Staphylococcus aureus (4), Staphylococcus aureus (3), unidentified (4). All 16 infections resolved without recurrence. Bony union was obtained in all cases. Fourteen out of 16 patients (87.5%) were completely relieved of pain and fully active, an excellent result according to Macnab's criteria; the other two patients obtained a good result. All 7 patients who had a neurological deficit improved. There were two superficial infections, which healed with debridement and antibiotics. A single iliac vein injury was primarily repaired. In conclusion, the proposed technique is an effective and safe treatment for pyogenic spondylodiscitis, if surgery is mandatory.
在出现神经功能损害、畸形、不稳定、脓肿形成、广泛破坏、顽固性疼痛或内科治疗失败的情况下,清创术适用于非结核性脊椎椎间盘炎的治疗。器械的额外使用仍存在争议,但可能有助于对抗感染并实现稳定。本回顾性研究的目的是评估16例非结核性胸腰椎脊椎椎间盘炎患者接受前路清创和重建(三面皮质骨移植或钛网笼),并结合一期后路器械固定和植骨的治疗效果。鉴定出的病原体为:布鲁氏菌(5例)、凝固酶阴性金黄色葡萄球菌(4例)、金黄色葡萄球菌(3例)、未明确(4例)。所有16例感染均痊愈且无复发。所有病例均实现了骨愈合。16例患者中有14例(87.5%)疼痛完全缓解且活动自如,根据Macnab标准为优秀结果;另外2例患者取得了良好结果。所有7例有神经功能缺损的患者均有改善。发生了2例表浅感染,经清创和抗生素治疗后愈合。1例髂静脉损伤进行了一期修复。总之,如果必须进行手术,所提出的技术是治疗化脓性脊椎椎间盘炎的一种有效且安全的方法。