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绝经后妇女报告的身高损失准确性及其身高损失的危险因素。

Accuracy of patient-reported height loss and risk factors for height loss among postmenopausal women.

机构信息

Department of Rheumatology, Hôpital Cochin and Université Paris Descartes, Paris, France.

出版信息

CMAJ. 2010 Apr 6;182(6):558-62. doi: 10.1503/cmaj.090710. Epub 2010 Mar 22.

Abstract

BACKGROUND

Since loss of height may indicate vertebral fracture, the accuracy of the information on height is relevant for clinical practice. We undertook this study to compare reported and measured loss of height among post-menopausal women in a primary care setting. We also analyzed the determinants of this height loss.

METHODS

In an observational study conducted between December 2007 and May 2008, we asked 1779 randomly selected general practitioners to recruit the first five female patients who were more than 60 years of age, regardless of the reason for the consultation. Using a questionnaire, physicians collected data on demographic and clinical variables, history of osteoporosis and current anti-osteoporotic treatment. We used three assessments of height: tallest height in early adulthood recalled by the patient, estimated current height reported by the patient at the visit and current measured height. We defined loss of height as the difference between the patient's tallest recalled height and her current measured height.

RESULTS

A total of 8610 patients were included in the analysis; the mean age was 70.9 (standard deviation [SD] 7.2) years. The mean loss of height was 4.5 cm. The mean current reported height was 2.1 (SD 2.5) cm lower than the tallest recalled height and 2.4 (SD 2.6) cm lower than the measured current height. The best predictors of a loss of height of 3 cm or more were age (odds ratio [OR] 1.09, 95% confidence interval [CI] 1.08-1.10), previous vertebral fracture (OR 1.49, 95% CI 1.16-1.91), previous nonvertebral fracture (OR 1.26, 95% CI 1.06-1.51), thoracic kyphosis (OR 2.07, 95% CI 1.69-2.55), scoliosis (OR 1.35, 95% CI 1.12-1.63), back pain (OR 1.22, 95% CI 1.07-1.39) and osteoporosis (OR 1.39, 95% CI 1.20-1.60).

INTERPRETATION

Our study showed that the patients' estimated current height was not correct, with a mean difference of -2.5 cm from the current measured height. The mean height loss was 4.5 cm. Previous vertebral fracture and thoracic kyphosis were strong determinants of the height loss.

摘要

背景

身高降低可能提示椎体骨折,因此临床实践中需要关注身高信息的准确性。本研究旨在比较绝经后女性在初级保健环境中报告的和测量的身高降低情况,并分析导致身高降低的因素。

方法

在 2007 年 12 月至 2008 年 5 月期间进行的一项观察性研究中,我们随机选择了 1779 名全科医生,要求他们招募首次就诊且年龄大于 60 岁的前 5 名女性患者,不论就诊原因。医生使用问卷收集患者的人口统计学和临床变量、骨质疏松症病史和当前抗骨质疏松症治疗情况。我们使用 3 种身高评估方法:患者回忆的年轻时最高身高、就诊时患者报告的当前估计身高和当前测量身高。我们将身高降低定义为患者最高回忆身高与当前测量身高之间的差值。

结果

共纳入 8610 例患者进行分析,患者的平均年龄为 70.9(标准差 7.2)岁。平均身高降低 4.5 cm。患者当前报告的身高平均比回忆的最高身高低 2.1(标准差 2.5)cm,比当前测量的身高低 2.4(标准差 2.6)cm。身高降低 3 cm 或更多的最强预测因素为年龄(比值比 1.09,95%置信区间 1.08-1.10)、既往椎体骨折(比值比 1.49,95%置信区间 1.16-1.91)、既往非椎体骨折(比值比 1.26,95%置信区间 1.06-1.51)、胸椎后凸(比值比 2.07,95%置信区间 1.69-2.55)、脊柱侧凸(比值比 1.35,95%置信区间 1.12-1.63)、背痛(比值比 1.22,95%置信区间 1.07-1.39)和骨质疏松症(比值比 1.39,95%置信区间 1.20-1.60)。

结论

我们的研究表明,患者估计的当前身高与当前测量的身高相差-2.5 cm,并不准确,平均身高降低 4.5 cm。既往椎体骨折和胸椎后凸是身高降低的重要决定因素。

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