Simeonov S, Ivanov V, Dimitrov A, Goranov Kh, Danov M
Vet Med Nauki. 1977;14(7):14-22.
Biochemical and histological investigations were carried out with cows affected with ketosis in a subclinical and clinical form. Parellel studies were performed with normal (control) cows originating from the herds with the ill animals and manifesting the same physiologic status. It was found that the blood level of glucose in the diseased cows was lowered more than 2.6 times, and the content of ketone bodies was higher-- it was increased 4.6 times, that of total lipids was 2.6 times higher, and that of free fatty acids was 3.5 times higher as compared to the same indices in the controls. The blood content of pyruvate in the affected cows was also increased. The liver glycogen in these animals was lowered from 2.1 to 4.1 times. The activity of glucose-6-phosphatase was lower, and that of glucose-6-phosphatedehydrogenase was higher as against the same indices shown by normal cows.
对患有亚临床和临床型酮病的奶牛进行了生化和组织学研究。对来自患病动物所在牛群且生理状态相同的正常（对照）奶牛进行了平行研究。结果发现，患病奶牛的血糖水平降低了2.6倍以上，酮体含量升高——与对照组相比增加了4.6倍，总脂质含量高2.6倍，游离脂肪酸含量高3.5倍。患病奶牛血液中丙酮酸的含量也有所增加。这些动物的肝糖原降低了2.1至4.1倍。与正常奶牛的相同指标相比，葡萄糖-6-磷酸酶的活性较低，而葡萄糖-6-磷酸脱氢酶的活性较高。
