Vasilov B
Vet Med Nauki. 1977;14(4):80-6.
Studied was the activity of the alkaline phosphatase and the transaminases in the serum of clinically normal and ketosis-affected cows as well as cows with an affected liver. The changes were followed in the activity of SGOT and SGPT that had set in as a result of five-day starving and the injection of prednisolon at the rate of 0.5 mg/kg in the course of four days. The activity of serum alkaline phosphatase in ketosis-affected cows proved unchanged--1.99 +/1 0.35 VE. A moderate increase was established in cows with liver affections-- 3.73 +/- 0.35 VE. The hyperenzymemia in ketosis-affected animals, in animals with liver injuries as well as in cows subjected to starving or prednisolon treatment was substantiated by the higher activity of SGOT. Dependable higher values of SGOT were established in the serum of freshly calved cows as compared to cows of advanced lactation. The higher activity of SGOT in animals with ketosis is associated with the physiologic status, starving, enzyme induction, inadequacy of the cell energy balance--all limiting the possibility of it being ascribed with preference to the tissue proliferation or destruction, which is to be expected with cows having an affected liver.
研究了临床正常、患酮病以及肝脏患病奶牛血清中碱性磷酸酶和转氨酶的活性。观察了因五日饥饿以及在四天内以0.5毫克/千克的剂量注射泼尼松龙而导致的谷草转氨酶（SGOT）和谷丙转氨酶（SGPT）活性的变化。患酮病奶牛血清碱性磷酸酶的活性未变——1.99±0.35欧洲单位（VE）。肝脏患病的奶牛出现了中度升高——3.73±0.35 VE。谷草转氨酶活性升高证实了患酮病动物、肝脏受损动物以及遭受饥饿或泼尼松龙治疗的奶牛存在酶血症。与处于泌乳后期的奶牛相比，刚产犊奶牛血清中的谷草转氨酶值可靠地更高。患酮病动物体内谷草转氨酶活性较高与生理状态、饥饿、酶诱导、细胞能量平衡不足有关——所有这些都限制了将其优先归因于组织增殖或破坏的可能性，而这在肝脏患病奶牛中是可以预期的。
