Interaction between cerulopasmin and Sendai virus envelope components. Note V. Serological response in the rabbit to Sendal virus and subviral fractions.

Immunization of rabbits with Sendai virus and subviral fractions induced the appearance in the serum of both hemagglutinin- and neuraminidase-inhibiting antibodies. The study of the correlation between antigen characteristics and the level and kinetics of the antibodies suggests that a single antigenic glycoprotein carries both hemagglutinin and neuraminidase activities. The level of serum antibodies depends both on the size and structure of the antigens and on their organization, and reflects the role of the protein and carbohydrate moieties of the different antigen preparations used.