仙台病毒在铜蓝蛋白和同源病毒包膜存在的情况下增殖。
Sendai virus multiplication in the presence of ceruloplasmin and homologous virus envelopes.
作者信息
Tomas E, Samuel I, Cajal N
出版信息
Acta Virol. 1979 May;23(3):221-5.
Preincubation of Sendai virus with ceruloplasmin induced in chorioallantoic membrane (CAM) fragments the synthesis of a population with decreased infectivity and high haemagglutinating (HA) and neuraminidase (NA) activities, whereas preincubation with solubilized virus envelopes led to the production of a viral population with the same infectivity as the control, but with lower HA and NA activities. Preincubation of the virus with a mixture of ceruloplasmin and solubilized envelopes depressed the overall virus synthesis; the resulting population had a low infectivity and high HA and NA activities. The variation in the HA/NA ratio indicates a modification in the envelope structure.
仙台病毒与铜蓝蛋白预孵育会导致鸡胚绒毛尿囊膜（CAM）片段中产生一群感染力降低但血凝（HA）和神经氨酸酶（NA）活性较高的病毒，而与溶解的病毒包膜预孵育则会产生一群与对照具有相同感染力但HA和NA活性较低的病毒。病毒与铜蓝蛋白和溶解包膜的混合物预孵育会抑制整体病毒合成；产生的病毒群体感染力低且HA和NA活性高。HA/NA比值的变化表明包膜结构发生了改变。
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