未免疫城市人群中甲型肝炎病毒和脊髓灰质炎病毒抗体的流行情况。

Prevalence of antibody to hepatitis A and polioviruses in an unimmunized urban population.

作者信息

Gust I D, Lewis F A, Lehmann N I

出版信息

Am J Epidemiol. 1978 Jan;107(1):54-6. doi: 10.1093/oxfordjournals.aje.a112507.

DOI:10.1093/oxfordjournals.aje.a112507

PMID:203186

Abstract

A large group of sera collected in 1954-1955 from people living in the metropolitan area of Melbourne, Australia, was tested for neutralizing antibody to polioviruses 1,2 and 3 and for antibody to hepatitis A virus by solid phase radioimmunoassay. The age-specific prevalence of antibody to each virus was remarkable similar, being highest in the elderly and in persons of low socioeconomic status. Antibody to each virus was acquired early in life, with more than half the population showing evidence of infection by the age of 15 years.

摘要

1954年至1955年期间，从澳大利亚墨尔本大都市区居民中采集了一大组血清样本，通过固相放射免疫分析法检测了针对脊髓灰质炎病毒1、2和3的中和抗体以及甲型肝炎病毒抗体。每种病毒抗体的年龄特异性流行率非常相似，在老年人和社会经济地位较低的人群中最高。每种病毒的抗体在生命早期就已获得，超过一半的人群在15岁时就有感染迹象。