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意大利托斯卡纳人群中针对脊髓灰质炎病毒的血清抗体

Serum antibodies to polioviruses in a Tuscan population, Italy.

作者信息

Reali D, Carducci A, Ruschi M A

机构信息

Dipartimento di Scienze dell'Ambiente e del Territorio, Università di Pisa, Italy.

出版信息

Eur J Epidemiol. 1990 Sep;6(3):309-12. doi: 10.1007/BF00150438.

Abstract

In order to study the serological status of a population against poliomyelitis, neutralizing antibody for the three types of polioviruses were examined in 742 serum specimens from individuals aged from 1 to 70 years and over were collected during 1985. Sixty-two percent of the sera had antibodies (titre greater than or equal to 1:8) to all three polioviruses, while 5% had no poliovirus antibody at all. However the rates of seropositivity did vary with age: the 10-19 age group had the lowest frequency of antibody (38%) to the three viruses and the difference between the percentage of this group and the previous (1-10 years) and following ones (20-70 years and over) was highly significant. The results of this seroprevalence survey indicate a gap in immunity to poliomyelitis in the population examined.

摘要

为研究某人群针对脊髓灰质炎的血清学状况,对1985年采集的742份年龄在1岁至70岁及以上个体的血清标本检测了三种脊髓灰质炎病毒的中和抗体。62%的血清对所有三种脊髓灰质炎病毒均有抗体(滴度大于或等于1:8),而5%的血清完全没有脊髓灰质炎病毒抗体。然而,血清阳性率确实随年龄而异:10 - 19岁年龄组对这三种病毒的抗体频率最低(38%),该组与前一组(1 - 10岁)及后一组(20 - 70岁及以上)的百分比差异非常显著。这项血清流行率调查结果表明,在所检测人群中脊髓灰质炎免疫存在差距。

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