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意大利城市人口对脊髓灰质炎病毒的血清免疫

Seroimmunity to polioviruses in an urban population of Italy.

作者信息

Volpi A, Ragona G, Biondi W, Rocchi G, Archetti I

出版信息

Bull World Health Organ. 1976;54(3):275-8.

Abstract

In a seroepidemiological survey on immunity to polioviruses, carried out in Rome, neutralizing antibodies were titrated on 602 serum samples collected from individuals aged from 6 months to 88 years. The geometric mean titres were 25.24, 25.92, and 18.12 for poliovirus types 1, 2, and 3, respectively. The number of seronegative results for each virus strain was very low (</=1.5%). The immune status of the study population could therefore be considered satisfactory. The distribution of antibody reactivity in different age groups was similar for poliovirus types 1 and 3, while for type 2 a significant difference in titres was found between adults and children.

摘要

在罗马进行的一项关于脊髓灰质炎病毒免疫力的血清流行病学调查中,对从6个月至88岁个体采集的602份血清样本进行了中和抗体滴定。脊髓灰质炎病毒1型、2型和3型的几何平均滴度分别为25.24、25.92和18.12。每种病毒株的血清阴性结果数量非常低(≤1.5%)。因此,研究人群的免疫状况可被认为是令人满意的。脊髓灰质炎病毒1型和3型在不同年龄组中的抗体反应性分布相似,而2型在成人和儿童之间的滴度存在显著差异。

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