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意大利城市人口对脊髓灰质炎病毒的血清免疫

Seroimmunity to polioviruses in an urban population of Italy.

作者信息

Volpi A, Ragona G, Biondi W, Rocchi G, Archetti I

出版信息

Bull World Health Organ. 1976;54(3):275-8.

PMID:191208
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2366572/
Abstract

In a seroepidemiological survey on immunity to polioviruses, carried out in Rome, neutralizing antibodies were titrated on 602 serum samples collected from individuals aged from 6 months to 88 years. The geometric mean titres were 25.24, 25.92, and 18.12 for poliovirus types 1, 2, and 3, respectively. The number of seronegative results for each virus strain was very low (</=1.5%). The immune status of the study population could therefore be considered satisfactory. The distribution of antibody reactivity in different age groups was similar for poliovirus types 1 and 3, while for type 2 a significant difference in titres was found between adults and children.

摘要

在罗马进行的一项关于脊髓灰质炎病毒免疫力的血清流行病学调查中,对从6个月至88岁个体采集的602份血清样本进行了中和抗体滴定。脊髓灰质炎病毒1型、2型和3型的几何平均滴度分别为25.24、25.92和18.12。每种病毒株的血清阴性结果数量非常低(≤1.5%)。因此,研究人群的免疫状况可被认为是令人满意的。脊髓灰质炎病毒1型和3型在不同年龄组中的抗体反应性分布相似,而2型在成人和儿童之间的滴度存在显著差异。

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1
Seroimmunity to polioviruses in an urban population of Italy.意大利城市人口对脊髓灰质炎病毒的血清免疫
Bull World Health Organ. 1976;54(3):275-8.
2
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3
Serological survey on immunity status against polioviruses in children and adolescents living in a border region, Apulia (Southern Italy).对居住在意大利南部普利亚大区一个边境地区的儿童和青少年针对脊髓灰质炎病毒的免疫状况进行的血清学调查。
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4
Vaccination against poliomyelitis in economically underdeveloped countries.经济欠发达国家的脊髓灰质炎疫苗接种
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Eur J Epidemiol. 1986 Sep;2(3):197-204. doi: 10.1007/BF00211532.
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Serum antibodies to polioviruses in a Tuscan population, Italy.意大利托斯卡纳人群中针对脊髓灰质炎病毒的血清抗体
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8
Antipoliomyelitis immunity status among a population that was regularly vaccinated 11-12 years before.11至12年前定期接种疫苗人群中的抗脊髓灰质炎免疫状况。
Eur J Epidemiol. 1991 Nov;7(6):605-11. doi: 10.1007/BF00218669.

本文引用的文献

1
[On the immunological situation seven years after the introduction into Italy of poliomyelitis vaccination with attenuated live virus vaccine].[关于减毒活疫苗脊髓灰质炎疫苗引入意大利七年后的免疫状况]
Ann Sclavo. 1973 Jan-Feb;15(1):1-18.
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[Immunitary defense against polioviruses in various population samples in several years following Sabin vaccination].[在服用沙宾疫苗后的数年间,不同人群样本对脊髓灰质炎病毒的免疫防御]
Ann Sclavo. 1971 May-Jun;13(3):391-410.
3
[Seroepidemiologic research on the antipoliomyelitic immunity in adult unvaccinated subjects].[未接种疫苗的成年人群中脊髓灰质炎抗病毒免疫的血清流行病学研究]
Boll Ist Sieroter Milan. 1975;54(6):472-5.