Unkle D, Smejkal R, Snyder R, Lessig M, Ross S E
Department of Surgery, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Cooper Hospital/University Medical Center, Camden.
Heart Lung. 1991 May;20(3):284-6.
The immediate transfusion of uncrossmatched type O blood in the initial resuscitation of the trauma victim remains controversial. To examine difficulties in crossmatching blood for later transfusions after use of uncrossmatched type O blood, we undertook a prospective 23-month study at a level I trauma center. One hundred thirty-five severely injured patients received uncrossmatched type O blood during the study period. Sixty-one patients (45%) died and 76 patients (56%) underwent emergent operation. There were no major transfusion reactions. Six patients had blood antigen-antibodies present on admission, and such antibodies developed in three patients during hospitalization. We conclude that uncrossmatched type O blood may be used safely in the exsanguinating patient, but blood antigen-antibodies, which may complicate later crossmatching, can develop after its use.
在创伤患者的初始复苏中立即输注未交叉配型的O型血仍存在争议。为了研究在使用未交叉配型的O型血后进行后续输血时交叉配血的困难，我们在一家一级创伤中心进行了一项为期23个月的前瞻性研究。在研究期间，135例重伤患者接受了未交叉配型的O型血。61例患者（45%）死亡，76例患者（56%）接受了急诊手术。未发生严重的输血反应。6例患者入院时存在血型抗原抗体，3例患者在住院期间产生了此类抗体。我们得出结论，未交叉配型的O型血可安全用于出血性休克患者，但使用后可能会出现血型抗原抗体，这可能会使后续交叉配血复杂化。
