Thomas L, Tuscany F L, Wilner G D
Arch Pathol Lab Med. 1981 Jan;105(1):52-3.
In 1979 we identified six patients in blood group A who were given non-group-specific platelets and who had difficulties in pretransfusion testing because of passively acquired antibodies to their own A antigen. In all six, results of earlier pretransfusion testing were unremarkable. Postplatelet transfusion findings consisted of the following: (1) negative result of screening for unexpected antibodies, (2) positive result from direct antiglobulin (Coombs') test, (3) incompatible cross match with group A RBCs, and (4) detection of anti-A antibody in each patient's serum and eluate. No clinical evidence of hemolysis was present in any of the patients. Identification of passively acquired ABO antibodies and selection of compatible blood can be facilitated by (1) accurate review of transfusion history for administration of non-group-specific blood products, (2) testing of eluate against group A, B, and O RBCs, and (3) cross match of patient's sera against group O donor RBCs.
1979年，我们鉴定出6例A型血患者，他们接受了非血型特异性血小板，并且由于被动获得针对自身A抗原的抗体，在输血前检测中遇到困难。在所有6例患者中，早期输血前检测结果均无异常。血小板输血后的结果如下：（1）意外抗体筛查结果为阴性；（2）直接抗球蛋白（库姆斯氏）试验结果为阳性；（3）与A型红细胞交叉配血不相容；（4）在每位患者的血清和洗脱液中检测到抗A抗体。所有患者均无溶血的临床证据。通过以下方法有助于鉴定被动获得的ABO抗体并选择相容血液：（1）准确回顾非血型特异性血液制品输血史；（2）用A、B和O型红细胞检测洗脱液；（3）将患者血清与O型供体红细胞进行交叉配血。
