Puig L, Esquius J, Fernández-Figueras M T, Moreno A, de Moragas J M
Department of Dermatology, Hospital de la Santa Creu i Santa Pau, Universidad Autónoma de Barcelona, Spain.
J Am Acad Dermatol. 1991 Apr;24(4):561-5. doi: 10.1016/0190-9622(91)70083-e.
Two cases of a hitherto undescribed special variant of dermatofibroma are reported. A man and a woman, aged 57 and 52 years, respectively, had slowly growing cutaneous tumors on the lower extremities. The tumors were exophytic and polypoid, 10 and 6 cm in maximal diameters, respectively; they were covered by rough nonulcerated skin and were joined by a short pedicle to an indurated base. Histologic examination showed some features of an otherwise conventional dermatofibroma, whereas the polypoid component was hypercellular and showed striking atypia and scattered mitotic figures. After 32 and 28 months' follow-up, the lesions did not recur after surgical excision. We suggest the term atypical polypoid dermatofibroma to summarize the special clinicopathologic features of these tumors.
报告了两例皮肤纤维瘤的一种迄今未描述的特殊变体。一名57岁男性和一名52岁女性分别在下肢有缓慢生长的皮肤肿瘤。肿瘤呈外生性和息肉样,最大直径分别为10厘米和6厘米;它们被粗糙的非溃疡性皮肤覆盖,并通过短蒂与硬结性基底相连。组织学检查显示出一些常规皮肤纤维瘤的特征,而息肉样成分细胞增多,并显示出明显的异型性和散在的有丝分裂象。经过32个月和28个月的随访,手术切除后病变未复发。我们建议用“非典型息肉样皮肤纤维瘤”这一术语来概括这些肿瘤的特殊临床病理特征。