Pusztaszeri Marc, Jaquet Pierre-Yves, Williamson Carole
Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland.
Case Rep Dermatol. 2011 Feb 18;3(1):32-6. doi: 10.1159/000324721.
Dermatofibroma is a common benign fibrohistiocytic lesion that usually appears as a slow-growing, firm dermal nodule with a predilection for the legs of middle-aged women. They are usually smaller than 2 cm in diameter. Many histological variants have been described. Generally, the clinical and histological diagnosis is straightforward, but differentiating it from other cutaneous tumors can be difficult in atypical cases and rare variants. Giant dermatofibroma is a rare clinical variant of dermatofibroma and less than 25 cases have been reported. It is characterized essentially by its unusually large size, which often mimics malignant tumors clinically. We first present the case of a giant hemosiderotic dermatofibroma in a 54-year-old patient, who presented with a large ulcerated mass of the left foot which was excised, and then review the literature briefly.
皮肤纤维瘤是一种常见的良性纤维组织细胞性病变,通常表现为生长缓慢、质地坚硬的真皮结节,好发于中年女性的腿部。其直径通常小于2cm。已描述了许多组织学变体。一般来说,临床和组织学诊断较为直接,但在非典型病例和罕见变体中,将其与其他皮肤肿瘤区分开来可能会很困难。巨大皮肤纤维瘤是皮肤纤维瘤的一种罕见临床变体,报道的病例少于25例。其主要特征是异常大的尺寸,临床上常类似恶性肿瘤。我们首先介绍一例54岁患者的巨大含铁血黄素沉着性皮肤纤维瘤病例,该患者左脚出现一个大的溃疡肿块,已被切除,然后简要回顾相关文献。