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COPD 的早期检测结合针对戒烟的个体化咨询:一项为期两年的前瞻性研究。

Early detection of COPD combined with individualized counselling for smoking cessation: a two-year prospective study.

机构信息

Department of Medicine, Division of Pulmonary Medicine, Lapland Central Hospital, Rovaniemi, Finlan.

出版信息

Scand J Prim Health Care. 2010 Mar;28(1):41-6. doi: 10.3109/02813431003630105.

Abstract

OBJECTIVE

Though the prevalence of COPD is related to the definition, even with this proviso COPD remains under-diagnosed. Screening can detect many new COPD cases, but its effects on smoking cessation remain unknown.

DESIGN

To evaluate symptoms in "healthy" cigarette smokers, to screen new COPD cases using international and national guidelines, and to assess the success of a smoking cessation.

SUBJECTS

Healthy asymptomatic smokers with a >20 pack-years smoking history were recruited. The first visit included a standardized personal interview, Fagerstom nicotine dependence test (FNDT) and individualized smoking counselling by Motivational Interviewing. At the follow-up visit two years later, the same analyses were repeated and smoking status assessed. To avoid bias in the counselling attributable to spirometry, the test was evaluated at the two-year follow-up assessment.

RESULTS

Almost all, 93.2%, of 584 participants attended the second visit. Spirometry revealed COPD by GOLD criteria in 11.0% and by national guidelines in 15.3%, mid-expiratory flow (MEF50) had significantly declined in 19.5%, chronic cough or sputum production was detected in 62% of the subjects. After two years, 23.3% had succeeded in giving up smoking. There were four predictors of successful quitting, i.e. positive attitude to the intervention, pharmacotherapy, older age, and higher BMI, whereas other factors such as cough, obstruction, gender, pack-years, or nicotine dependence showed no association with ability to achieve successful cessation.

CONCLUSION

Significant numbers of "healthy" smokers experience symptoms, according to detailed questionnaires, and have COPD. Motivation is the most significant factor in determining the chance of stopping smoking.

摘要

目的

尽管 COPD 的流行与定义有关,但即使有此规定,COPD 的诊断仍不足。筛查可以发现许多新的 COPD 病例,但它对戒烟的影响尚不清楚。

设计

评估“健康”吸烟人群的症状,使用国际和国家指南筛查新的 COPD 病例,并评估戒烟的成功。

对象

招募了有>20 包年吸烟史的无症状健康吸烟者。首次就诊包括标准化的个人访谈、Fagerstom 尼古丁依赖测试(FNDT)和由动机访谈提供的个性化吸烟咨询。两年后的随访访问中,重复了相同的分析,并评估了吸烟状况。为避免因肺功能检查导致咨询偏倚,该测试在两年后的评估中进行。

结果

584 名参与者中几乎所有人(93.2%)都参加了第二次就诊。GOLD 标准和国家指南显示,肺功能检查发现 11.0%和 15.3%的患者患有 COPD,中呼气流量(MEF50)显著下降了 19.5%,62%的患者出现慢性咳嗽或咳痰。两年后,23.3%的人成功戒烟。成功戒烟的四个预测因素是,即对干预措施的积极态度、药物治疗、年龄较大和更高的 BMI,而其他因素,如咳嗽、阻塞、性别、包年或尼古丁依赖,与戒烟成功的能力无关。

结论

根据详细的问卷,相当数量的“健康”吸烟者出现症状,并患有 COPD。动机是决定戒烟成功机会的最重要因素。

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