实验感染微小膜壳绦虫的白化小鼠的病理和免疫病理变化。
Pathological and immunopathological changes in albino mice experimentally infected with Hymenolepis nana.
作者信息
Mangoud A M, Eissa M H, Abdallah M A, Hassan M M, Sabry A H, Fikry A A, Morsy T A
机构信息
Department of Pathology, Faculty of Medicine, Zagazig University, Egypt.
出版信息
J Egypt Soc Parasitol. 1991 Apr;21(1):43-51.
The pathological and immunopathological effects of H. nana on experimentally infected albino mice were studied, sacrificed one, three and five months post egg inoculation. The results showed that most of the mice had diarrhoea, loss of appetite and were inactive. On the other hand, the liver and spleen showed some pathological changes and cysticercoids were seen particularly in the liver. The kidneys showed cloudy swelling (3/90). The brain showed oedema (15/90) and glyosis (15/90). Intestinal atrophy and ulceration were very marked (30/90) with negative reaction to PAS and Alcian blue stain. Cysticercoids were seen in intestinal villi. The immunoglobulins in sections of the S. intestine changed from moderate to negative (IgA) or to mild (IgM) or from mild to marked (IgG). The whole results were discussed.
研究了微小膜壳绦虫对实验感染的白化小鼠在虫卵接种后1个月、3个月和5个月处死时的病理和免疫病理影响。结果显示，大多数小鼠出现腹泻、食欲不振和活动减少。另一方面，肝脏和脾脏出现了一些病理变化，尤其在肝脏中可见似囊尾蚴。肾脏出现混浊肿胀（3/90）。大脑出现水肿（15/90）和神经细胞溶解（15/90）。肠道萎缩和溃疡非常明显（30/90），对PAS和阿尔辛蓝染色呈阴性反应。在肠绒毛中可见似囊尾蚴。小肠切片中的免疫球蛋白从适度变为阴性（IgA）或轻度（IgM），或从轻度变为显著（IgG）。对整个结果进行了讨论。
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