Yoshizawa K, Fukumoto T, Hori T, Miura K, Morita J
Department of Respiratory Surgery, Takamatsu Red Cross Hospital, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1991 Feb;39(2):204-8.
A 6-year-old girl with mediastinal ganglioneuroma was reported. Preoperative examinations revealed that the tumor had both secretive activity of catecholamine and uptake of 131-I-MIBG. Clinical symptom was only supraventricular premature beat on ECG. The tumor, which was located at the left upper mediastinum, was well encapsulated. Total surgical removal was accomplished. Subsequently serum and urine levels of catecholamine were normalized. Detailed histological examination of the tumor revealed benign ganglioneuroma. No blastic change was recognized. We postulate that secretive activity of catecholamine and uptake of 131-I-MIBG cannot suggest malignancy necessarily.
报告了一名患有纵隔神经节细胞瘤的6岁女孩。术前检查显示该肿瘤具有儿茶酚胺分泌活性和131-I-间碘苄胍摄取。临床症状仅为心电图上的室上性早搏。肿瘤位于左上纵隔，包膜完整。手术完整切除。随后儿茶酚胺的血清和尿液水平恢复正常。对肿瘤进行详细的组织学检查显示为良性神经节细胞瘤。未发现母细胞样改变。我们推测儿茶酚胺分泌活性和131-I-间碘苄胍摄取不一定提示恶性。
