Applied Imaging Science Laboratory, Department of Radiology, Brigham and Women's Hospital, Boston, MA, USA.
Int J Cardiovasc Imaging. 2010 Aug;26(6):683-91. doi: 10.1007/s10554-010-9621-4. Epub 2010 Mar 24.
The purpose of this study is to primarily evaluate the lumen area and secondarily evaluate wall area measurements of in vivo lower extremity peripheral vein bypass grafts patients using high spatial resolution, limited field of view, cardiac gated, black blood inner volume three-dimensional fast spin echo MRI. Fifteen LE-PVBG patients prospectively underwent ultrasound followed by T1-weighted and T2-weighted magnetic resonance (MR) imaging. Lumen and vessel wall areas were measured by direct planimetry. For graft lumen areas, T1- and T2-weighted measurements were compared with ultrasound. For vessel wall areas, differences between T1- and T2-weighted measurements were evaluated. There was no significant difference between ultrasound and MR lumen measurements, reflecting minimal MR blood suppression artifact. Graft wall area measured from T1-weighted images was significantly larger than that measured from T2-weighted images (P < 0.001). The mean of the ratio of T1- versus T2-weighted vessel wall areas was 1.59 (95% CI: 1.48-1.69). The larger wall area measured on T1-weighted images was due to a significantly larger outer vessel wall boundary. Very high spatial resolution LE-PVBG vessel wall MR imaging can be performed in vivo, enabling accurate measurements of lumen and vessel wall areas and discerning differences in those measures between different tissue contrast weightings. Vessel wall area differences suggest that LE-PVBG vessel wall tissues produce distinct signal characteristics under T1 and T2 MR contrast weightings.
本研究的目的主要是评估高空间分辨率、有限视野、心脏门控、黑血内体积三维快速自旋回波 MRI 对活体下肢外周静脉旁路移植术患者的管腔面积，次要评估血管壁面积。15 例下肢外周静脉旁路移植术患者前瞻性地进行了超声检查，随后进行了 T1 加权和 T2 加权磁共振（MR）成像。通过直接平面测量法测量管腔和血管壁面积。对于移植物管腔面积，比较了 T1 加权和 T2 加权测量值与超声测量值。对于血管壁面积，评估了 T1 加权和 T2 加权测量值之间的差异。超声和 MR 管腔测量值之间无显著差异，反映出最小的 MR 血液抑制伪影。T1 加权图像测量的移植物壁面积明显大于 T2 加权图像测量的面积（P < 0.001）。T1 加权与 T2 加权血管壁面积比值的平均值为 1.59（95%CI：1.48-1.69）。T1 加权图像上测量的较大壁面积归因于较大的外血管壁边界。非常高的空间分辨率下肢外周静脉旁路移植术血管壁 MR 成像可在活体中进行，能够准确测量管腔和血管壁面积，并区分不同组织对比加权之间这些测量值的差异。血管壁面积差异表明，下肢外周静脉旁路移植术血管壁组织在 T1 和 T2 MR 对比加权下产生明显不同的信号特征。
