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A型肉毒毒素注射后序贯石膏固定对改善慢性卒中患者马蹄内翻畸形的疗效。

The efficacy of serial casting after botulinum toxin type A injection in improving equinovarus deformity in patients with chronic stroke.

作者信息

Yaşar Evren, Tok Fatih, Safaz Ismail, Balaban Birol, Yilmaz Bilge, Alaca Ridvan

机构信息

Gulhane Military Medical Academy, Department of Physical Medicine and Rehabilitation, GMMA TAF Rehabilitation Center, Ankara, Turkey.

出版信息

Brain Inj. 2010;24(5):736-9. doi: 10.3109/02699051003610524.

Abstract

INTRODUCTION

Spasticity is an important early complication of stroke, which may lead to shortening of gastrocnemius and soleus muscles and contracture in the Achilles tendon and soft tissues of the ankle. Botulinum toxin A (BTX-A) is a promising drug for the management of focal spasticity. Serial casting is another alternative method for reducing contractures due to spasticity. The present study aimed to determine if serial casting after BTX-A injection could help to limit the development of calf contracture in chronic hemiplegic patients.

METHOD

The records of patients with stroke that were treated in the brain injury rehabilitation clinic between January 2007 and December 2008 were screened. In all, 10 patients that underwent a serial casting programme for 24 days following BTX-A injection were included in the study. Goniometric scores for ankle ROM, Physician Rating Scale (PRS) and Functional Independence Measurement (FIM) scores were recorded.

RESULTS

Mean age of the patients was 33.2 years. Mean time interval after stroke onset was 35.0 months. Improvements in ROM were quite significant after serial casting. Moreover, FIM and PRS scores improved significantly.

CONCLUSION

Serial casting may be an appropriate intervention following BTX-A injection to prevent equinovarus deformity and improve the quality of walking in chronic stroke patients. The role of casting and splinting are important topics that require further research.

摘要

引言

痉挛是中风后的一种重要早期并发症,可能导致腓肠肌和比目鱼肌缩短以及跟腱和踝关节软组织挛缩。A型肉毒毒素(BTX-A)是一种用于治疗局灶性痉挛的有前景的药物。连续石膏固定是另一种减轻因痉挛导致挛缩的替代方法。本研究旨在确定BTX-A注射后进行连续石膏固定是否有助于限制慢性偏瘫患者小腿挛缩的发展。

方法

筛选2007年1月至2008年12月期间在脑损伤康复诊所接受治疗的中风患者记录。共有10名患者在BTX-A注射后接受了为期24天的连续石膏固定方案,并纳入本研究。记录踝关节活动度的角度测量评分、医生评定量表(PRS)和功能独立性测量(FIM)评分。

结果

患者的平均年龄为33.2岁。中风发作后的平均时间间隔为35.0个月。连续石膏固定后活动度有相当显著的改善。此外,FIM和PRS评分也有显著改善。

结论

连续石膏固定可能是BTX-A注射后一种合适的干预措施,以预防马蹄内翻畸形并改善慢性中风患者的步行质量。石膏固定和夹板固定的作用是需要进一步研究的重要课题。

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