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A型肉毒毒素注射后石膏固定、缠绷带或拉伸治疗痉挛性马蹄内翻足:一项成年脑卒中患者的单盲随机临床试验。

Casting, taping or stretching after botulinum toxin type A for spastic equinus foot: a single-blind randomized trial on adult stroke patients.

机构信息

Physical and Rehabilitative Medicine, Azienda Ospedaliera Universitaria Maggiore della Carità, Novara, Italy.

出版信息

Clin Rehabil. 2011 Dec;25(12):1119-27. doi: 10.1177/0269215511405080. Epub 2011 Jul 5.

DOI:10.1177/0269215511405080
PMID:21729974
Abstract

OBJECTIVE

To investigate the effect of different adjunctive treatments after botulinum toxin type A.

DESIGN

Single-blind, randomized trial, with three-month follow-up.

SETTING

Secondary rehabilitative care.

SUBJECTS

Convenience sample of 69 chronic hemiplegic adult patients with spastic equinus foot.

INTERVENTIONS

Following botulinum toxin type A injection at the plantar flexors, patients were randomly assigned to three groups and treated with either taping, casting or stretching for one week, and with stretching and gait training for the next week.

OUTCOME MEASURES

Modified Ashworth Scale at plantar flexors, passive range of motion at the ankle, six-minute walking test, 10-metre walking test, Functional Ambulation Categories, ankle dorsiflexor strength were evaluated before treatment (t(0)) at 20 days (t(1)) and 90 days (t(2)) after treatment.

RESULTS

At t(1) only the taping and casting groups showed significant improvements in Modified Ashworth Scale, six-minute walking test, 10-metre walking test and passive range of motion (P < 0.02). At t(2), while the results were maintained in the casting group, only six-minute walking test and Modified Ashworth Scale were still significantly improved in the taping group. Ankle dorsiflexor strength and Functional Ambulation Categories did not change in any of the groups at any time. At t(2) the casting group performed better than the taping and stretching groups at Modified Ashworth Scale and passive range of motion, and better than the stretching group at six-minute walking test (P < 0.02).

CONCLUSIONS

Combining botulinum toxin type A to the ankle plantar flexors with casting or taping gives better and longer lasting results than with stretching alone.

摘要

目的

研究肉毒毒素 A 辅助治疗后的效果。

设计

单盲、随机试验,随访 3 个月。

地点

二级康复治疗。

对象

方便选取的 69 例慢性偏瘫成人痉挛性马蹄内翻足患者。

干预措施

在跟腱注射肉毒毒素 A 后,患者随机分为三组,分别接受为期一周的绷扎、固定或伸展治疗,以及随后一周的伸展和步态训练。

结果

在治疗前(t(0))、治疗后 20 天(t(1))和 90 天(t(2)),分别采用改良 Ashworth 量表评估踝关节跖屈肌、被动关节活动度、6 分钟步行测试、10 米步行测试、功能性步行分类和踝背屈肌力量。结果显示,仅绷扎和固定组在改良 Ashworth 量表、6 分钟步行测试、10 米步行测试和被动关节活动度方面有显著改善(P<0.02)。在 t(2)时,虽然固定组的结果得以维持,但只有绷扎组的 6 分钟步行测试和改良 Ashworth 量表仍有显著改善。在任何时间,各组的踝背屈肌力量和功能性步行分类都没有变化。在 t(2)时,固定组在改良 Ashworth 量表和被动关节活动度方面优于绷扎和伸展组,在 6 分钟步行测试方面优于伸展组(P<0.02)。

结论

与单独伸展相比,将肉毒毒素 A 与踝关节跖屈肌结合绷扎或固定治疗可获得更好、更持久的效果。

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