Brasnu E, Dupas B, Hoang-Xuan T, Baudouin C, Gatinel D
Service d'Ophtalmologie III, Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris.
J Fr Ophtalmol. 2010 Apr;33(4):264.e1-5. doi: 10.1016/j.jfo.2010.01.014. Epub 2010 Mar 24.
Schnyder's crystalline corneal dystrophy is a rare bilateral hereditary disease with various clinical features. It typically presents as a central disc-like opacification with or without crystalline deposits. We report the case of a particular crystalline-free and ring-like pattern dystrophy resembling Schnyder's corneal dystrophy in an 82-year-old woman. In addition, we describe the aspects of this dystrophy with in vivo confocal microscopy using the Heidelberg Retina Tomograph II-Rostock Cornea Module and with anterior segment optical coherence tomography (OCT-Visante((R))). These techniques can be useful in the diagnosis or the therapeutic process, showing crystalline structures that are not clinically distinguishable or validating the histological localization of the corneal disease.
施奈德结晶性角膜营养不良是一种罕见的双侧遗传性疾病,具有多种临床特征。它通常表现为中央盘状混浊,伴有或不伴有结晶沉积物。我们报告了一例82岁女性患有一种特殊的无结晶且呈环状的营养不良,类似于施奈德角膜营养不良。此外,我们使用海德堡视网膜断层扫描仪II - 罗斯托克角膜模块的活体共聚焦显微镜和眼前节光学相干断层扫描(OCT - Visante((R)))描述了这种营养不良的情况。这些技术在诊断或治疗过程中可能有用,可显示临床上无法区分的结晶结构或验证角膜疾病的组织学定位。