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伴有周边角膜变性的基质性角膜营养不良(可能为施奈德角膜营养不良)——诊断与治疗挑战

Stromal corneal dystrophy (possible Schnyder's dystrophy) with peripheral corneal degeneration - diagnostic and therapeutic challenges.

作者信息

Zemba Mihail, Neacsa Raluca, Cucu Bogdan Ion

机构信息

Department of Ophthalmology, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania.

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

Rom J Ophthalmol. 2018 Apr-Jun;62(2):175-180.

Abstract

to highlight the diagnostic and therapeutic challenges in a case with central and peripheral corneal lesions. We present the preoperative investigations: anterior segment optical coherence tomography and ultrasound biomicroscopy; The excised cornea has been examined histopathologically. Preoperative assessment showed that peripheral lesion was not ectatic; Histopathological examination points to a possible corneal degeneration, with posttraumatic or infectious etiology for the peripheral lesion and gives some reasons to sustain the diagnosis of Schnyder's dystrophy for the central lesion. The association of different corneal lesions may need many investigations to establish the diagnosis and choose the most appropriate therapeutic solution.

摘要

以突出一例伴有中央和周边角膜病变病例中的诊断和治疗挑战。我们展示了术前检查:眼前节光学相干断层扫描和超声生物显微镜检查;对切除的角膜进行了组织病理学检查。术前评估显示周边病变并非扩张性病变;组织病理学检查表明可能存在角膜变性,周边病变的病因是创伤后或感染性的,并且有一些理由支持中央病变为施奈德营养不良的诊断。不同角膜病变的联合可能需要多项检查来确立诊断并选择最合适的治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f932/6117528/64c1ed4ce43f/RomJOphthalmol-62-175-g001.jpg

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