Department of Clinical Veterinary Medicine, Anaesthesiology Division, Vetsuisse-Faculty, University of Berne, 3012 Berne, Switzerland.
Vet J. 2011 Apr;188(1):53-7. doi: 10.1016/j.tvjl.2010.02.008. Epub 2010 Mar 23.
The aim of this study was to describe the sciatic-femoral nerve block (SFNB) in goats and to evaluate the peri-operative analgesia when the goats underwent stifle arthrotomy. The animals were randomly assigned to one of four treatment groups: groups 0.25, 0.5 and 0.75 received 0.25%, 0.5% and 0.75% of bupivacaine, respectively, while group C (control group) received 0.9% NaCl. In all groups, the volume administered was 0.2 mL/kg. Intra-operatively, the proportion of animals receiving rescue propofol was significantly lower in groups 0.5 and 0.75, compared to group C. Post-operatively, the visual analogue scale (VAS) and total pain score were significantly higher in group C than in the other groups. Group 0.75 had the highest percentage of animals showing motor blockade. SFNB performed with bupivacaine resulted in better intra- and post-operative analgesia than SFNB performed with saline. Compared to the other concentrations, 0.5% bupivacaine resulted in satisfactory analgesia with acceptable side effects.
本研究旨在描述山羊坐骨-股神经阻滞（SFNB），并评估山羊行膝关节切开术时该神经阻滞的围手术期镇痛效果。动物被随机分配到四个治疗组之一：0.25%、0.5%和 0.75%布比卡因组分别接受 0.25%、0.5%和 0.75%布比卡因，而 C 组（对照组）接受 0.9%生理盐水。所有组的给药体积均为 0.2 mL/kg。术中，与 C 组相比，0.5%和 0.75%布比卡因组接受解救性异丙酚的动物比例明显更低。术后，C 组的视觉模拟评分（VAS）和总疼痛评分明显高于其他组。0.75%布比卡因组出现运动阻滞的动物比例最高。与生理盐水相比，SFNB 中使用布比卡因可获得更好的围手术期镇痛效果。与其他浓度相比，0.5%布比卡因具有令人满意的镇痛效果和可接受的副作用。
