Fonseca Carla, Server Anna, Esteves Marielle, Barastegui David, Rosal Marta, Fontecha Cesar G, Soldado Francisco
Experimental Surgery Unit, Vall d'Hebron Research Institute, Barcelona, Spain.
Department of Anesthesiology, Vall d'Hebron Universitary Hospital, Barcelona, Spain.
Lab Anim (NY). 2015 May;44(5):179-84. doi: 10.1038/laban.732.
Regional anesthesia techniques, such as nerve blocks, are routinely used in humans and can contribute to multimodal approaches to pain management in research animals. Ultrasound guidance is an emerging aspect of regional anesthesia that has the potential to optimize local delivery and distribution of anesthetic agents, thereby reducing the amounts of these agents that must be administered. The authors developed an ultrasound-guided technique for effective block of the axillary brachial plexus in rabbits. They used this technique to carry out nerve block in 14 rabbits. The procedure was accomplished in a relatively short amount of time and achieved successful nerve block in all rabbits with no adverse effects. Sonographic visualization of the distribution of the local anesthetic ropivacaine led to administration of smaller anesthetic doses in eight of the rabbits without affecting the duration of nerve block. The authors conclude that their technique is feasible and safe and provides effective analgesia of the thoracic limb in rabbits. They recommend that this technique be integrated into multimodal approaches to pain management in rabbits undergoing thoracic limb surgery.
区域麻醉技术，如神经阻滞，在人类中常规使用，并且可有助于在实验动物中采用多模式疼痛管理方法。超声引导是区域麻醉的一个新兴方面，它有可能优化麻醉剂的局部递送和分布，从而减少必须给予的这些药物的量。作者开发了一种用于有效阻滞兔腋部臂丛神经的超声引导技术。他们使用该技术对14只兔进行神经阻滞。该操作在相对较短的时间内完成，并且在所有兔中均成功实现神经阻滞，无不良影响。局部麻醉药罗哌卡因分布的超声可视化使得8只兔中使用了较小的麻醉剂量，而不影响神经阻滞的持续时间。作者得出结论，他们的技术是可行且安全的，并能为兔的胸肢提供有效的镇痛。他们建议将该技术纳入接受胸肢手术的兔的多模式疼痛管理方法中。
