Key Laboratory of Tropical Crop Biotechnology, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, Hainan, China.
Molecules. 2010 Jan 27;15(2):606-12. doi: 10.3390/molecules15020606.
Chemical investigation of the EtOH extract of the twigs of Calophyllum inophyllum collected in Hainan Province of China resulted in the isolation of two new prenylated xanthones, caloxanthone O (1) and caloxanthone P (2). Their structures were elucidated by a study of their physical and spectral data. Compound 1 exhibited cytotoxicity against human gastric cancer cell line (SGC-7901),with an IC50 value of 22.4 microg mL-1.
从中国海南省采集的红厚壳树枝的乙醇提取物的化学研究导致了两种新的类柠檬素的分离,即考罗黄烷酮 O(1)和考罗黄烷酮 P(2)。通过对其物理和光谱数据的研究,阐明了它们的结构。化合物 1 对人胃癌细胞系(SGC-7901)表现出细胞毒性,IC50 值为 22.4μg/mL-1。