Centre for Occupational and Environmental Health, Health Sciences Research Group, School of Community Based Medicine, University of Manchester, Oxford Road, Manchester M139PL, UK.
J Expo Sci Environ Epidemiol. 2010 Jul;20(5):399-405. doi: 10.1038/jes.2010.8. Epub 2010 Mar 24.
Environmental exposure to high-frequency voltage transients (HFVT), also termed dirty electricity, has been advocated among electro(hyper)sensitive interest groups as an important biological active component of standard electromagnetic pollution. A literature search was conducted in PubMed, in which only seven articles were identified. Exposure to HFVT was associated with increased cancer risks, while preferential removal of 4-100 kHz HFVT from 50-60 Hz ELF circuits was linked to a variety of improvements in health (plasma glucose levels in diabetic patients, symptoms of multiple sclerosis, asthma and other respiratory illnesses, and insomnia), well-being (tiredness, frustration, general health, irritation, sense of satisfaction, mood), and student behavior. However, all these published studies were subject to significant methodological flaws in the design of the studies, the assessment of exposure, and the statistical analysis, which prevented valid assessment of a causal link between this exposure metric and adverse effects. Environmental exposure to HFVT is an interesting EMF exposure metric, which might explain the spurious results from epidemiological studies using 'standard' ELF and RF exposure metrics. However, at present, methodological problems in published studies prohibit the valid assessment of its biological activity.
环境中高频电压瞬变(HFVT)的暴露,也称为“脏电”,在电(超)敏感利益群体中被认为是标准电磁污染中一个重要的生物活性成分。在 PubMed 中进行了文献检索,仅确定了 7 篇文章。HFVT 的暴露与癌症风险的增加有关,而将 4-100 kHz 的 HFVT 优先从 50-60 Hz 的 ELF 电路中去除,则与健康(糖尿病患者的血浆葡萄糖水平、多发性硬化症、哮喘和其他呼吸道疾病以及失眠)、幸福感(疲劳、沮丧、总体健康、烦躁、满足感、情绪)和学生行为的各种改善有关。然而,所有这些已发表的研究都存在研究设计、暴露评估和统计分析方面的重大方法学缺陷,这使得无法有效评估这种暴露指标与不良影响之间的因果关系。环境中 HFVT 的暴露是一个有趣的电磁场暴露指标,它可能解释了使用“标准”ELF 和射频暴露指标的流行病学研究中出现的虚假结果。然而,目前,已发表研究中的方法学问题阻止了对其生物活性的有效评估。