[人氟斑牙体外脱矿与再矿化的研究]

[Study on demineralization and remineralization of human fluorosed teeth in vitro].

作者信息

Luo Liya, Li Hong, Liang Jichao, Lei Xiaoxue, Zhang Hui, Peng Shengcheng, Liang Chengwen

机构信息

State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Feb;27(1):116-9, 125.

PMID:20337037

Abstract

This study sought to determine the impact of dental fluorosis severity on demineralization and remineralization of human fluorosed teeth in vitro. Surface enamel microhardness was measured on the enamel blocks before and after demineralization and after remineralization. The results showed that after demineralization, the sequence of % Surface microhardness demineralization (% SMHD) was TFI4 (18.92 +/- 1.31) < TFI3 (20.50 +/- 1.32) < TFI2 (25.08 +/- 1.69) < TFI1 (27.77 +/- 1.79) < TFI0 (30.70 +/- 1.35) (P < 0.05), and there was no statistically significant differences between TFI1 (27.77 +/- 1.79) and the normal group TFI0 (30.70 +/- 1.35). After remineralization, the sequence of % Surface microhardness remineralization (% SMHR) was TFI1 (55.17 +/- 1.23) > TFI0 (53.97 +/- 3.05) > TFI2 (49.17 +/- 1.81) > TFI3 (44.85 +/- 1.89) > TFI4 (36.51 +/- 2.95) (P < 0.05). Moderately fluorosed enamel showed a significatnt resistance to caries, but mildly fluorosed enamel could get better remineralization. These facts and figures deserve clinicians' attention.

摘要

本研究旨在确定氟斑牙严重程度对人体氟斑牙体外脱矿和再矿化的影响。在脱矿前、脱矿后以及再矿化后，测量牙釉质块的表面釉质显微硬度。结果显示，脱矿后，表面显微硬度脱矿百分比（%SMHD）的顺序为TFI4（18.92±1.31）＜TFI3（20.50±1.32）＜TFI2（25.08±1.69）＜TFI1（27.77±1.79）＜TFI0（30.70±1.35）（P＜0.05），且TFI1（27.77±1.79）与正常组TFI0（30.70±1.35）之间无统计学显著差异。再矿化后，表面显微硬度再矿化百分比（%SMHR）的顺序为TFI1（55.17±1.23）＞TFI0（53.97±3.05）＞TFI2（49.17±1.81）＞TFI3（44.85±1.89）＞TFI4（36.51±2.95）（P＜0.05）。中度氟斑牙釉质对龋齿有显著抗性，但轻度氟斑牙釉质能获得更好的再矿化。这些事实和数据值得临床医生关注。