Armstrong R W
Community Hospital of Los Gatos-Saratoga, California.
J Urol. 1991 Jun;145(6):1264-6. doi: 10.1016/s0022-5347(17)38596-8.
Two cases of adverse reaction to bacillus Calmette-Guerin (BCG) bladder instillations are reported. In both cases transient fevers and systemic symptoms developed following the instillations. After an additional instillation 1 patient had high fevers, severe myalgias and profound weakness followed by rhabdomyolysis and anuric renal failure, which required 3 weeks of hemodialysis before recovery. Extensive evaluation revealed no cause other than the BCG instillations. In the other patient a firm subcutaneous nodule gradually developed on the chest wall, which contained nonviable acid fast bacilli.
报告了两例卡介苗（BCG）膀胱灌注不良反应的病例。两例患者在灌注后均出现短暂发热和全身症状。在再次灌注后，1例患者出现高热、严重肌痛和极度虚弱，随后发生横纹肌溶解和无尿性肾衰竭，恢复前需要进行3周的血液透析。广泛评估显示，除卡介苗灌注外无其他病因。另一例患者胸壁上逐渐出现一个坚实的皮下结节，结节内含有无活性的抗酸杆菌。
