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卡介苗膀胱灌注诱发的肌病表现为横纹肌溶解：一例报告

Intravesical bacillus Calmette-Guérin-induced myopathy presenting as rhabdomyolysis: a case report.

作者信息

Lee Chae Hun, Choi Byeong Joo, Kim Jung Hun, Yang Tae Woong, Kim Gi Jeong, Shin Ha Young, Kim Se Hoon, Kim Seung Woo

机构信息

Yonsei University College of Medicine, Seoul, Korea.

Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

出版信息

J Yeungnam Med Sci. 2023 Oct;40(4):430-434. doi: 10.12701/jyms.2022.00850. Epub 2023 Feb 13.

DOI:10.12701/jyms.2022.00850
PMID:36775925
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10626292/
Abstract

Intravesical bacillus Calmette-Guérin (BCG) instillation is an adjuvant treatment for non-muscle-invasive urinary bladder cancer. Although most complications associated with BCG immunotherapy are mild and self-limiting, rare albeit serious complications have been reported. Only a few cases of BCG-related rhabdomyolysis have been reported. In this study, we present the case of a 72-year-old woman who developed severe weakness and hyperCKemia following intravesical BCG instillation. A muscle biopsy was performed, and a diagnosis of drug-induced myopathy was made.

摘要

膀胱内灌注卡介苗（BCG）是非肌层浸润性膀胱癌的辅助治疗方法。尽管与BCG免疫疗法相关的大多数并发症是轻微的且具有自限性，但仍有罕见但严重的并发症报道。仅报告了少数几例与BCG相关的横纹肌溶解症病例。在本研究中，我们报告了一例72岁女性在膀胱内灌注BCG后出现严重肌无力和高肌酸激酶血症的病例。进行了肌肉活检，并诊断为药物性肌病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1d7/10626292/b96f4d2486fe/jyms-2022-00850f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1d7/10626292/65257d25625d/jyms-2022-00850f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1d7/10626292/4e4bc73ca5c6/jyms-2022-00850f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1d7/10626292/b96f4d2486fe/jyms-2022-00850f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1d7/10626292/65257d25625d/jyms-2022-00850f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1d7/10626292/4e4bc73ca5c6/jyms-2022-00850f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1d7/10626292/b96f4d2486fe/jyms-2022-00850f3.jpg

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