Miller Emily S, Hoekstra Anna V, Hurteau Jean A, Rodriguez Gustavo C
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Northwestern Feinberg School of Medicine, Chicago, Illinois, USA.
J Reprod Med. 2010 Jan-Feb;55(1-2):78-80.
Disease metastatic to the heart from cervical carcinoma is rare and associated with a poor prognosis. Multimodality treatment has been shown to provide palliative benefit.
A woman presented with stage Ib2 cervical cancer metastatic to the tricuspid valve. She presented with small bowel obstruction from a small bowel metastasis 4 years after initial treatment with chemoradiation. Computed tomographic imaging revealed a small bowel mass as well as a pericardial effusion. Cardiac magnetic resonance imaging showed a tricuspid mass. Endomyocardial biopsy confirmed metastatic disease consistent with a cervical primary. The patient was treated with bowel resection, systemic chemotherapy and cardiac radiation. She died of cardiac failure 8 months after diagnosis of the cardiac lesion.
Cervical cancer metastatic to the heart is rare and associated with a poor prognosis. Selected patients may benefit from multimodality treatment.
宫颈癌转移至心脏罕见,且预后较差。多模式治疗已显示可提供姑息性益处。
一名女性患者,患有Ib2期宫颈癌并转移至三尖瓣。在初始放化疗治疗4年后,她因小肠转移出现小肠梗阻。计算机断层扫描成像显示小肠肿块以及心包积液。心脏磁共振成像显示三尖瓣肿块。心内膜活检证实为与宫颈原发灶一致的转移性疾病。该患者接受了肠切除术、全身化疗和心脏放疗。在诊断出心脏病变8个月后,她死于心力衰竭。
宫颈癌转移至心脏罕见,且预后较差。部分患者可能从多模式治疗中获益。