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宫颈低分化癌的心脏转移:一例报告

Cardiac metastasis from poorly differentiated carcinoma of the cervix: a case report.

作者信息

Miller Emily S, Hoekstra Anna V, Hurteau Jean A, Rodriguez Gustavo C

机构信息

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Northwestern Feinberg School of Medicine, Chicago, Illinois, USA.

出版信息

J Reprod Med. 2010 Jan-Feb;55(1-2):78-80.

PMID:20337214
Abstract

BACKGROUND

Disease metastatic to the heart from cervical carcinoma is rare and associated with a poor prognosis. Multimodality treatment has been shown to provide palliative benefit.

CASE

A woman presented with stage Ib2 cervical cancer metastatic to the tricuspid valve. She presented with small bowel obstruction from a small bowel metastasis 4 years after initial treatment with chemoradiation. Computed tomographic imaging revealed a small bowel mass as well as a pericardial effusion. Cardiac magnetic resonance imaging showed a tricuspid mass. Endomyocardial biopsy confirmed metastatic disease consistent with a cervical primary. The patient was treated with bowel resection, systemic chemotherapy and cardiac radiation. She died of cardiac failure 8 months after diagnosis of the cardiac lesion.

CONCLUSION

Cervical cancer metastatic to the heart is rare and associated with a poor prognosis. Selected patients may benefit from multimodality treatment.

摘要

背景

宫颈癌转移至心脏罕见,且预后较差。多模式治疗已显示可提供姑息性益处。

病例

一名女性患者,患有Ib2期宫颈癌并转移至三尖瓣。在初始放化疗治疗4年后,她因小肠转移出现小肠梗阻。计算机断层扫描成像显示小肠肿块以及心包积液。心脏磁共振成像显示三尖瓣肿块。心内膜活检证实为与宫颈原发灶一致的转移性疾病。该患者接受了肠切除术、全身化疗和心脏放疗。在诊断出心脏病变8个月后,她死于心力衰竭。

结论

宫颈癌转移至心脏罕见,且预后较差。部分患者可能从多模式治疗中获益。

相似文献

1
Cardiac metastasis from poorly differentiated carcinoma of the cervix: a case report.宫颈低分化癌的心脏转移:一例报告
J Reprod Med. 2010 Jan-Feb;55(1-2):78-80.
2
Cardiac metastasis from carcinoma of the cervix: report of two cases.子宫颈癌的心脏转移:两例报告。
Gynecol Oncol. 1998 Jun;69(3):264-8. doi: 10.1006/gyno.1998.5009.
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Isolated cardiac metastasis of cervical carcinoma presenting as disseminated intravascular coagulopathy. A case report.以弥散性血管内凝血为表现的宫颈癌孤立性心脏转移:一例报告
J Reprod Med. 2000 Jul;45(7):603-6.
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Rare metastases of recurrent cervical cancer to the pericardium and abdominal muscle.复发性宫颈癌罕见转移至心包和腹部肌肉。
Arch Gynecol Obstet. 2008 Nov;278(5):479-82. doi: 10.1007/s00404-008-0602-y. Epub 2008 Feb 26.
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Advanced cervical squamous cell carcinoma with skin metastasis.晚期宫颈鳞状细胞癌伴皮肤转移。
Taiwan J Obstet Gynecol. 2007 Sep;46(3):264-6. doi: 10.1016/S1028-4559(08)60031-5.
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Hemiballismus and brain metastases from squamous cell carcinoma of the cervix.偏身投掷症与子宫颈鳞状细胞癌脑转移
Gynecol Oncol. 1999 Nov;75(2):289-92. doi: 10.1006/gyno.1999.5551.
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Concomitant chemoradiation prior to surgery in the treatment of advanced cervical carcinoma.晚期宫颈癌手术前同步放化疗。
Gynecol Oncol. 1994 Jul;54(1):68-75. doi: 10.1006/gyno.1994.1168.
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Rapid manifestation of CNS metastatic disease in a cervical carcinoma patient: a case report.一名宫颈癌患者中枢神经系统转移性疾病的快速表现:病例报告
Oncology. 2007;73(3-4):273-6. doi: 10.1159/000127426. Epub 2008 Apr 17.
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Metastatic carcinoma of the gallbladder mimicking an advanced cervical carcinoma.酷似晚期宫颈癌的胆囊转移性癌。
Gynecol Oncol. 2005 Jun;97(3):942-5. doi: 10.1016/j.ygyno.2005.01.054. Epub 2005 Apr 13.
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Pericardial metastasis in carcinoma of the uterine cervix.子宫颈癌的心包转移
Gynecol Oncol. 1996 Jun;61(3):451-3. doi: 10.1006/gyno.1996.0174.

引用本文的文献

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Cardiac metastasis in uterine cervical cancer : A systematic review and case study.子宫颈癌的心脏转移:一项系统评价与病例研究
Strahlenther Onkol. 2025 Jan;201(1):71-81. doi: 10.1007/s00066-024-02274-y. Epub 2024 Sep 17.
2
Cardiac metastasis of uterine cervical squamous cell carcinoma: A case report and review of the literature.子宫颈鳞状细胞癌的心脏转移:一例报告并文献复习
J Cardiol Cases. 2014 Sep 2;10(6):221-225. doi: 10.1016/j.jccase.2014.08.001. eCollection 2014 Dec.
3
Cardiac metastasis in cervical cancer.宫颈癌的心脏转移
BJR Case Rep. 2016 May 25;2(2):20150300. doi: 10.1259/bjrcr.20150300. eCollection 2016.
4
Biventricular metastatic invasion from cervical squamous cell carcinoma.宫颈鳞状细胞癌的双心室转移浸润
BMJ Case Rep. 2016 Jul 1;2016:bcr2016214931. doi: 10.1136/bcr-2016-214931.
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A case of cardiac metastasis from uterine cervical carcinoma.一例子宫颈癌心脏转移病例。
Case Rep Obstet Gynecol. 2015;2015:703424. doi: 10.1155/2015/703424. Epub 2015 Feb 24.
6
Intracardiac metastasis from known cervical cancer: a case report and literature review.心内转移的已知宫颈癌:病例报告及文献复习。
World J Surg Oncol. 2013 May 23;11:107. doi: 10.1186/1477-7819-11-107.