Department of Dermatology, Peking University Third Hospital, Beijing, China.
Mycoses. 2011 Jul;54(4):e136-42. doi: 10.1111/j.1439-0507.2010.01859.x. Epub 2010 Mar 22.
During the past four decades, seven patients were documented in China to have died from Exophiala infections. Causative agents were Exophiala dermatitidis, Exophiala spinifera, Exophiala jeanselmei and a new Exophiala species, Exophiala asiatica. We retrospectively analysed the clinical characteristics of these infections in China and confirmed the identity of aetiological agents of Chinese fatal cases using rDNA ITS sequence analysis. While E. dermatitidis displayed neurotropism, E. spinifera showed osteotropism. The other two species, E. jeanselmei and E. asiatica had caused brain infections in China.
在过去的四十年中，中国有七名患者死于外瓶霉属感染。病原体为皮炎外瓶霉、棘状外瓶霉、詹氏外瓶霉和一种新的外瓶霉属物种，即亚洲外瓶霉。我们回顾性分析了这些感染在中国的临床特征，并通过 rDNA ITS 序列分析确认了中国致死病例的病原体。皮炎外瓶霉具有神经趋向性，棘状外瓶霉具有骨趋向性。另外两种，詹氏外瓶霉和亚洲外瓶霉，在中国引起了脑部感染。
