Pannunzio Eliana, Amancio Olga Maria Silverio, Vitalle Maria Sylvia de Souza, Souza Douglas Nesadal de, Mendes Fausto Medeiros, Nicolau José
Departamento de Pediatria, Universidade Federal de São Paulo UNIFESP, São Paulo, SP.
Rev Assoc Med Bras (1992). 2010 Jan-Feb;56(1):32-6. doi: 10.1590/s0104-42302010000100012.
To determine if some stimulated whole saliva parameters are influenced by an increase of Body Mass Index.
Controlled cross-sectional study involving 90 school children of both genders between 7 and 10 years of age, from Bragança Paulista - SP. Three groups were formed: overweight, obese and control. Body Mass Index and diet intake by the Food Register method were evaluated. The salivary pH, flow rate, buffer capacity, protein, phosphate, calcium, fluoride, total and free sialic acid, and peroxidase activity were determined.
The overweight and obese groups showed greater energy and lipid intake (P< 0.001) than the control group. There was no difference in the saliva flow rate between groups, however only the control group showed a mean value considered normal. In the overweight and obese groups a decrease in both the concentration of phosphate (P< 0.001) and peroxidase activity (P<0.001) was observed. In the obese group an increase in the concentrations of free sialic acid (P= 0.004) and protein (P= 0.003) occurred.
Overweight and obese children show alterations in the concentrations of phosphate, free sialic acid and proteins, and in the peroxidase activity that are favorable conditions for dental caries.
确定体重指数的增加是否会影响某些刺激全唾液参数。
对来自圣保罗州布拉干萨保利斯塔市的90名7至10岁的学龄儿童进行对照横断面研究。研究对象分为三组：超重组、肥胖组和对照组。采用食物登记法评估体重指数和饮食摄入量。测定唾液的pH值、流速、缓冲能力、蛋白质、磷酸盐、钙、氟化物、总唾液酸和游离唾液酸以及过氧化物酶活性。
超重组和肥胖组的能量和脂质摄入量高于对照组（P<0.001）。各组间唾液流速无差异，但只有对照组的平均值被认为是正常的。在超重组和肥胖组中，观察到磷酸盐浓度（P<0.001）和过氧化物酶活性（P<0.001）均降低。在肥胖组中，游离唾液酸浓度（P=0.004）和蛋白质浓度（P=0.003）增加。
超重和肥胖儿童的磷酸盐、游离唾液酸和蛋白质浓度以及过氧化物酶活性发生改变，这些都是导致龋齿的有利条件。
