纯化的人T淋巴细胞群体对爱泼斯坦-巴尔病毒（EBV）的增殖反应。
Blastogenic response of purified human T-lymphocyte populations to Epstein-Barr virus (EBV).
作者信息
Gergely P, Ernberg I, Klein G, Steinitz M
出版信息
Clin Exp Immunol. 1977 Dec;30(3):347-53.
Abstract
The blastogenic response of T-cell populations to infectious EBV (B95-8 strain) was studied. The addition of virus increased the [3H]thymidine uptake of unfractionated lymphocytes from seropositive and seronegative subjects, and from cord blood, but not from patients with infectious mononucleosis. The same amount of virus evoked a small response in purified T cells from seropositive donors, but not in T cells from the other sources. The addition of autologous B lymphocytes with EBV adsorbed on their surfaces caused a more significant blastogenic response, which was even more pronounced in the presence of mercaptoethanol.
摘要
研究了T细胞群体对感染性EB病毒（B95 - 8株）的增殖反应。添加病毒可增加血清阳性和血清阴性受试者以及脐带血中未分级淋巴细胞的[3H]胸苷摄取，但感染性单核细胞增多症患者的淋巴细胞除外。等量的病毒在血清阳性供体的纯化T细胞中引起轻微反应，但在其他来源的T细胞中则无反应。添加表面吸附有EB病毒的自体B淋巴细胞会引起更显著的增殖反应，在存在巯基乙醇的情况下这种反应更为明显。
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