传染性单核细胞增多症患者对爱泼斯坦-巴尔病毒转化细胞的混合淋巴细胞培养反应。
The MLC response of patients with infectious mononucleosis to Epstein-Barr virus-transformed cells.
作者信息
Wasik M, Myc A, Matej H, Rudzka L
出版信息
Arch Immunol Ther Exp (Warsz). 1983;31(6):871-8.
PMID:6331340
Abstract
Lymphocytes of 6 patients with infectious mononucleosis were found to be capable of responding in mixed lymphocyte culture (MLC) to Epstein-Barr virus (EBV)--transformed lymphoblastoid cell lines and Raji cells, whereas their response to PWM-induced blasts and non-T cells was significantly depressed. This means that despite the suppression of cellular reactivity, observed in infectious mononucleosis, the specific response to EBV-infected cells remains unaffected.
摘要
研究发现，6例传染性单核细胞增多症患者的淋巴细胞在混合淋巴细胞培养（MLC）中能够对爱泼斯坦-巴尔病毒（EBV）转化的淋巴母细胞系和拉吉细胞作出反应，而它们对PWM诱导的母细胞和非T细胞的反应则显著降低。这意味着，尽管在传染性单核细胞增多症中观察到细胞反应性受到抑制，但对EBV感染细胞的特异性反应仍未受影响。
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