Department of Radiation Epidemiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Biomarkers. 2010 Jun;15(4):340-4. doi: 10.3109/13547501003735532.
The leptin:adiponectin ratio (L:A ratio) is an independent predictor of carotid intima-media thickness (CIMT).
To evaluate whether the leptin:high-molecular-weight adiponectin ratio (L:HA ratio) is associated with CIMT in the general population.
We investigated the relationship between the L:HA ratio and CIMT in 233 Japanese study participants (106 men and 127 women).
After adjustment for confounding factors, CIMT was significantly correlated with the log L:HA ratio (beta = 0.11, p = 0.014) in men, whereas no correlation was observed in women (beta = 0.01, p = 0.50).
The L:HA ratio is closely correlated with CIMT in men, but not in women.
瘦素：高分子量脂联素比值（L:A 比值）是颈动脉内膜中层厚度（CIMT）的独立预测因子。
评估瘦素：高分子量脂联素比值（L:HA 比值）与普通人群 CIMT 的关系。
我们调查了 233 名日本研究参与者（106 名男性和 127 名女性）中 L:HA 比值与 CIMT 之间的关系。
在调整混杂因素后，男性的 CIMT 与 log L:HA 比值呈显著相关（β=0.11，p=0.014），而女性则无相关性（β=0.01，p=0.50）。
L:HA 比值与男性的 CIMT 密切相关，但与女性无关。
