J Assoc Nurses AIDS Care. 2010 May-Jun;21(3):256-64. doi: 10.1016/j.jana.2010.01.005. Epub 2010 Mar 29.
Despite disproportionate rates of HIV among transgender women and evidence that medication adherence is necessary for treatment success and increased likelihood of survival, there has been little investigation into antiretroviral therapy (ART) adherence issues among transgender women. This study examined rates of self-reported ART adherence among transgender women on ART (n = 35) and well-established correlates of nonadherence, including depression, adherence self-efficacy, patient perceptions of interactions with their providers, and perceived adverse side effects of ART compared to other respondents (n = 2,770). Transgender women on ART were less likely to report 90% adherence rates or higher and reported less confidence in their abilities to integrate treatment regimens into their daily lives. When transgender women were compared to other respondents, regardless of the current medication regimen, they reported significantly fewer positive interactions with their health care providers. Training for providers and integration of hormone therapy into HIV care is recommended.
尽管跨性别女性感染艾滋病毒的比例不成比例，而且有证据表明，坚持用药对于治疗成功和提高生存几率是必要的，但针对跨性别女性抗逆转录病毒治疗（ART）依从性问题的研究却很少。本研究调查了正在接受抗逆转录病毒治疗的跨性别女性（n = 35）自我报告的 ART 依从性率，以及与不依从相关的既定因素，包括抑郁、依从自我效能、患者对与提供者互动的看法，以及与其他应答者相比对 ART 的不良反应感知（n = 2,770）。正在接受抗逆转录病毒治疗的跨性别女性报告的 90%以上依从率较低，对自己将治疗方案融入日常生活的能力的信心较低。与其他应答者相比，无论目前的药物治疗方案如何，跨性别女性报告与他们的医疗服务提供者的积极互动明显较少。建议对提供者进行培训，并将激素治疗纳入 HIV 护理。
