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苍白密螺旋体亚种芝加哥株的全基因组序列和注释。

Complete genome sequence and annotation of the Treponema pallidum subsp. pallidum Chicago strain.

机构信息

Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington 98195, USA.

出版信息

J Bacteriol. 2010 May;192(10):2645-6. doi: 10.1128/JB.00159-10. Epub 2010 Mar 26.

DOI:10.1128/JB.00159-10
PMID:20348263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2863575/
Abstract

In syphilis research, the Nichols strain of Treponema pallidum, isolated in 1912, has been the most widely studied. Recently, important differences among T. pallidum strains emerged; therefore, we sequenced and annotated the Chicago strain genome to facilitate and encourage the use of this strain in studying the pathogenesis of syphilis.

摘要

在梅毒研究中，1912 年分离出的Nichols 株苍白密螺旋体是研究最多的。最近，苍白密螺旋体菌株之间出现了重要差异；因此，我们对芝加哥株基因组进行了测序和注释，以促进和鼓励使用该菌株来研究梅毒的发病机制。

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