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QA-driven guidelines generation for bacteriotherapy.

作者信息

Pasche Emilie, Teodoro Douglas, Gobeill Julien, Ruch Patrick, Lovis Christian

机构信息

Medical Informatics Service, University Hospitals of Geneva and University of Geneva.

出版信息

AMIA Annu Symp Proc. 2009 Nov 14;2009:509-13.

Abstract

PURPOSE

We propose a question-answering (QA) driven generation approach for automatic acquisition of structured rules that can be used in a knowledge authoring tool for antibiotic prescription guidelines management.

METHODS

The rule generation is seen as a question-answering problem, where the parameters of the questions are known items of the rule (e.g. an infectious disease, caused by a given bacterium) and answers (e.g. some antibiotics) are obtained by a question-answering engine.

RESULTS

When looking for a drug given a pathogen and a disease, top-precision of 0.55 is obtained by the combination of the Boolean engine (PubMed) and the relevance-driven engine (easyIR), which means that for more than half of our evaluation benchmark at least one of the recommended antibiotics was automatically acquired by the rule generation method.

CONCLUSION

These results suggest that such an automatic text mining approach could provide a useful tool for guidelines management, by improving knowledge update and discovery.

摘要

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本文引用的文献

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Automatic medical encoding with SNOMED categories.使用SNOMED分类进行自动医学编码。
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The epidemiology of antibiotic resistance.抗生素耐药性的流行病学
Int J Antimicrob Agents. 2008 Nov;32 Suppl 1:S2-9. doi: 10.1016/j.ijantimicag.2008.06.016. Epub 2008 Aug 30.
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Epidemiological observations of the judicious use of antibiotics in a pediatric teaching hospital.
Int J Infect Dis. 2002 Mar;6(1):74-7. doi: 10.1016/s1201-9712(02)90141-4.
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Use of antibiotic agents in a large teaching hospital. The impact of Antibiotic Guidelines.
Med J Aust. 1983 Sep 3;2(5):217-21. doi: 10.5694/j.1326-5377.1983.tb122427.x.

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